PMID- 8972782
OWN - NLM
STAT- MEDLINE
DCOM- 19970320
LR  - 20161018
IS  - 0892-7790 (Print)
IS  - 0892-7790 (Linking)
VI  - 10
IP  - 6
DP  - 1996 Dec
TI  - Side effects of high-energy shockwaves in the human kidney: first experience with 
      model comparing two shockwave sources.
PG  - 507-11
AB  - The side effects of high-energy shockwaves (HESW) from two different sources on 
      kidney parenchyma obtained from 10 patients treated by radical nephrectomy for 
      renal cell carcinoma were examined. Immediately after nephrectomy, the kidneys 
      were perfused with cold HTK solution and kept in hypothermia (8 degrees C) for a 
      maximum of 4 hours. In five cases, the tumor-free parenchyma was treated at the 
      upper or lower renal pole with 2000 shocks, energy output 21 kV, in an 
      experimental electromagnetic shockwave system (Siemens Co., Erlangen). In the 
      other five cases, the upper or lower poles were treated with 2000 shocks, energy 
      output 24 kV, in an electrohydraulic spark gap system (MFL 5000; Dornier 
      Medizintechnik, Germering). The resulting tissue defects were analyzed by 
      histologic examinations. Changes after treatment with the electromagnetic system 
      were found mainly in the tubules and midsized blood vessels in a well-defined 
      focal area. Treatment with the electrohydraulic system was followed by tubular 
      and glomerular lesions combined with vessel defects in a patchy pattern. The 
      model is able to define the side effects of HESW in the human kidney and to test 
      the side effects of different lithotripters.
FAU - Roessler, W
AU  - Roessler W
AD  - Urology Department, Hospital St. Josef, Regensburg, Germany.
FAU - Wieland, W F
AU  - Wieland WF
FAU - Steinbach, P
AU  - Steinbach P
FAU - Hofstaedter, F
AU  - Hofstaedter F
FAU - Thuroff, S
AU  - Thuroff S
FAU - Chaussy, C
AU  - Chaussy C
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - J Endourol
JT  - Journal of endourology
JID - 8807503
SB  - IM
MH  - Aged
MH  - Carcinoma, Renal Cell/pathology/radiotherapy/surgery
MH  - Female
MH  - High-Energy Shock Waves/*adverse effects
MH  - Humans
MH  - In Vitro Techniques
MH  - Kidney/pathology/*radiation effects
MH  - Kidney Neoplasms/pathology/radiotherapy/surgery
MH  - Lithotripsy/adverse effects/instrumentation
MH  - Male
MH  - Middle Aged
MH  - Nephrectomy
EDAT- 1996/12/01 00:00
MHDA- 1996/12/01 00:01
CRDT- 1996/12/01 00:00
PHST- 1996/12/01 00:00 [pubmed]
PHST- 1996/12/01 00:01 [medline]
PHST- 1996/12/01 00:00 [entrez]
AID - 10.1089/end.1996.10.507 [doi]
PST - ppublish
SO  - J Endourol. 1996 Dec;10(6):507-11. doi: 10.1089/end.1996.10.507.