PMID- 8976373
OWN - NLM
STAT- MEDLINE
DCOM- 19970122
LR  - 20211025
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 92
IP  - 2
DP  - 1996 Dec
TI  - Trisomies 8 and 20 in desmoid tumors.
PG  - 147-9
AB  - A nonrandom occurrence of trisomy 8 and of trisomy 20 in desmoid tumors has been 
      recently reported. The finding of trisomy 8 in nondividing desmoid tumor cells by 
      in situ hybridization prompted us to evaluate, in a similar way, the occurrence 
      of trisomy 20 and the possible occurrence of both trisomies together because 
      their co-existence was cytogenetically observed in a few cases. Double 
      fluorescence in situ hybridization (FISH) with centromeric probes for chromosomes 
      8 and 20 was performed on 16 single cell suspensions of desmoid tumors. FISH 
      confirmed the occurrence of trisomy 8 or 20 in a single cell suspension of 
      desmoid tumors. Both individual trisomies, and even more their association in the 
      same cells, are rare to extremely rare in solid tumors in general and in 
      mesenchymal tumors in particular, and are only known to occur in infantile 
      fibrosarcoma.
FAU - Qi, H
AU  - Qi H
AD  - Center for Human Genetics, University of Leuven, Belgium.
FAU - Dal Cin, P
AU  - Dal Cin P
FAU - Hernandez, J M
AU  - Hernandez JM
FAU - Garcia, J L
AU  - Garcia JL
FAU - Sciot, R
AU  - Sciot R
FAU - Fletcher, C
AU  - Fletcher C
FAU - Van Eyken, P
AU  - Van Eyken P
FAU - De Wever, I
AU  - De Wever I
FAU - Van den Berghe, H
AU  - Van den Berghe H
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
SB  - IM
CIN - Cancer Genet Cytogenet. 1996 Dec;92(2):150-1. PMID: 8976374
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Child, Preschool
MH  - *Chromosomes, Human, Pair 20
MH  - *Chromosomes, Human, Pair 8
MH  - Female
MH  - Fibromatosis, Aggressive/*genetics/*pathology
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Male
MH  - *Trisomy
EDAT- 1996/12/01 00:00
MHDA- 1996/12/01 00:01
CRDT- 1996/12/01 00:00
PHST- 1996/12/01 00:00 [pubmed]
PHST- 1996/12/01 00:01 [medline]
PHST- 1996/12/01 00:00 [entrez]
AID - S0165460896001707 [pii]
AID - 10.1016/s0165-4608(96)00170-7 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1996 Dec;92(2):147-9. doi: 10.1016/s0165-4608(96)00170-7.