PMID- 8990479
OWN - NLM
STAT- MEDLINE
DCOM- 19970228
LR  - 20151119
IS  - 0006-8969 (Print)
IS  - 0006-8969 (Linking)
VI  - 48
IP  - 12
DP  - 1996 Dec
TI  - [Super selective amytal test for functional evaluation of the brain--a less 
      invasive functional test].
PG  - 1121-5
AB  - In the neurosurgical field, it is very important to evaluate localized function 
      of the affected region preoperatively. In order to investigate lateralized and 
      localized brain function, we have developed an alternative to the original Wada 
      test, and refer to it as the super selective amytal test (SSAT). We performed 
      super selective catheterization of the target artery after conventional carotid 
      angiography, injected Amytal (amobarbital, 30-100 mg) through a micro-catheter, 
      and identified potential local function. In ten cases, including AVM, aneurysm, 
      and brain tumor, we investigated localized function of the affected site 
      preoperatively by SSAT, and chose our treatment based on the results of this 
      test. There was a good correlation between the results of the SSAT and the 
      results of surgery in every case. There were no prolonged neurological 
      complications of this test. Evaluation of the results of the SSAT should be 
      interpreted under precise DSA control, since blood flow in the brain differ among 
      individuals. This test may contribute to our knowledge of localized function in 
      the cerebral cortex and deep brain areas in neurosurgical patients.
FAU - Kinoshita, Y
AU  - Kinoshita Y
AD  - Department of Neurological Surgery, Wakayama Medical College, Japan.
FAU - Maeshima, S
AU  - Maeshima S
FAU - Terada, T
AU  - Terada T
FAU - Nakai, E
AU  - Nakai E
FAU - Itakura, T
AU  - Itakura T
FAU - Komai, N
AU  - Komai N
LA  - jpn
PT  - Case Reports
PT  - Clinical Trial
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - No To Shinkei
JT  - No to shinkei = Brain and nerve
JID - 0413550
RN  - GWH6IJ239E (Amobarbital)
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Amobarbital/administration & dosage
MH  - Brain Diseases/diagnosis
MH  - *Cerebral Angiography
MH  - Cerebral Arteries
MH  - Female
MH  - Humans
MH  - Injections, Intra-Arterial
MH  - Male
MH  - *Neuropsychological Tests
EDAT- 1996/12/01 00:00
MHDA- 1996/12/01 00:01
CRDT- 1996/12/01 00:00
PHST- 1996/12/01 00:00 [pubmed]
PHST- 1996/12/01 00:01 [medline]
PHST- 1996/12/01 00:00 [entrez]
PST - ppublish
SO  - No To Shinkei. 1996 Dec;48(12):1121-5.