PMID- 8995479 OWN - NLM STAT- MEDLINE DCOM- 19970130 LR - 20180214 IS - 0301-0171 (Print) IS - 0301-0171 (Linking) VI - 75 IP - 1 DP - 1996 TI - High-resolution FISH mapping of beta-defensin genes to river buffalo and sheep chromosomes suggests a chromosome discrepancy in ffttle standard karyotypes. PG - 10-3 AB - High-resolution chromosomal fluorescence in situ hybridization (FISH) and R-banding allowed the chromosomal localization of the beta-defensin gene cluster (DEFB@) to chromosome band 1p12 in the river buffalo (Bubalus bubalis, 2n = 50) and to band 24q13 in sheep (Ovis aries, 2n = 54), according to standard nomenclatures. The localizations permitted the tentative assignment of the entire bovine syntenic group U25 to these chromosomes. A FISH mapping control on cattle chromosomes confirmed the localization of DEFB@ in the homoeologous chromosome and chromosome band. Comparisons were made between river buffalo chromosome 1p and the homoeologous cattle chromosome on standard karyotypes; the results are discussed in light of gene assignments, extensive chromosome band conservation among the Bovidae, and inconsistencies in domestic cattle chromosome nomenclatures. FAU - Iannuzzi, L AU - Iannuzzi L AD - National Research Council (CNR), IABBAM, Naples, Italy. FAU - Gallagher, D S AU - Gallagher DS FAU - Di Meo, G P AU - Di Meo GP FAU - Diamond, G AU - Diamond G FAU - Bevins, C L AU - Bevins CL FAU - Womack, J E AU - Womack JE LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, Non-P.H.S. PL - Switzerland TA - Cytogenet Cell Genet JT - Cytogenetics and cell genetics JID - 0367735 RN - 0 (Blood Proteins) RN - 0 (Defensins) RN - 0 (Genetic Markers) SB - IM MH - Animals MH - Blood Proteins/*genetics MH - Buffaloes/*genetics MH - Cattle/*genetics MH - Chromosome Banding MH - *Chromosome Mapping MH - Defensins MH - Genetic Markers MH - In Situ Hybridization, Fluorescence MH - Karyotyping MH - *Multigene Family MH - Sheep/*genetics MH - Terminology as Topic EDAT- 1996/01/01 00:00 MHDA- 1996/01/01 00:01 CRDT- 1996/01/01 00:00 PHST- 1996/01/01 00:00 [pubmed] PHST- 1996/01/01 00:01 [medline] PHST- 1996/01/01 00:00 [entrez] AID - 10.1159/000134446 [doi] PST - ppublish SO - Cytogenet Cell Genet. 1996;75(1):10-3. doi: 10.1159/000134446.