PMID- 8996059 OWN - NLM STAT- MEDLINE DCOM- 19970130 LR - 20190718 IS - 0004-8682 (Print) IS - 0004-8682 (Linking) VI - 66 IP - 12 DP - 1996 Dec TI - Thirty years experience with heart valve surgery: isolated mitral valve replacement. PG - 806-12 AB - BACKGROUND: Thirty years have elapsed since the commencement of open-heart surgery in South Australia. A retrospective study was performed to evaluate mortality and complication rates and to identify factors associated with poor outcomes in all patients who underwent prosthetic mitral valve replacement during this period. METHODS: Questionnaires and personal contact have been used to generate a combined database of pre-operative and post-operative information and long-term follow-up on 938 patients who underwent isolated prosthetic mitral valve replacement at the Cardio-Thoracic Surgical Unit of the Royal Adelaide Hospital between 1963 and 1993. RESULTS: Complete survival follow-up data were obtained for 92% (865) of the patients. The Starr-Edwards valve was used in 95% (891) of the patients, a Bjork-Shiley prosthesis in 2.5% (23) of the patients, and only 24 (2.5%) other valves were inserted. The hospital mortality rate for the 30-year period was 4.7%. The mean age of the patients who underwent surgery was greater in each of the three successive decades. A long-term survival advantage was observed for patients with mitral stenosis, however, survival was significantly shorter for patients with higher New York Heart Association (NYHA) functional classifications and for patients in pre-operative atrial fibrillation. Pre-operative dyspnoea was significantly improved following mitral valve replacement. The rates of postoperative haemorrhagic and embolic complications were low by comparison with other published series. CONCLUSION: Mitral valve recipients do not regain a normalized life expectancy, but risk factors that determine long-term survival can be identified pre-operatively to aid appropriate patient selection. FAU - Bessell, J R AU - Bessell JR AD - Cardio-Thoracic Surgical Unit, Royal Adelaide Hospital, North Terrace, Australia. FAU - Gower, G AU - Gower G FAU - Craddock, D R AU - Craddock DR FAU - Stubberfield, J AU - Stubberfield J FAU - Maddern, G J AU - Maddern GJ LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Australia TA - Aust N Z J Surg JT - The Australian and New Zealand journal of surgery JID - 0373115 SB - IM CIN - Aust N Z J Surg. 1997 Nov;67(11):809; author reply 810-1. PMID: 9397002 CIN - Aust N Z J Surg. 1997 Nov;67(11):809-10; author reply 810-1. PMID: 9397003 MH - Adolescent MH - Aged MH - Aged, 80 and over MH - Child MH - Female MH - Follow-Up Studies MH - *Heart Valve Prosthesis MH - Hemorrhage/epidemiology MH - Hospital Mortality MH - Hospitalization MH - Humans MH - Male MH - Middle Aged MH - Mitral Valve/surgery MH - Mitral Valve Insufficiency/*surgery MH - Mitral Valve Stenosis/*surgery MH - Postoperative Complications MH - Reoperation MH - Survival Rate MH - Thromboembolism/epidemiology EDAT- 1996/12/01 00:00 MHDA- 1996/12/01 00:01 CRDT- 1996/12/01 00:00 PHST- 1996/12/01 00:00 [pubmed] PHST- 1996/12/01 00:01 [medline] PHST- 1996/12/01 00:00 [entrez] AID - 10.1111/j.1445-2197.1996.tb00754.x [doi] PST - ppublish SO - Aust N Z J Surg. 1996 Dec;66(12):806-12. doi: 10.1111/j.1445-2197.1996.tb00754.x.