PMID- 9012616 OWN - NLM STAT- MEDLINE DCOM- 19970220 LR - 20041117 IS - 1081-1206 (Print) IS - 1081-1206 (Linking) VI - 78 IP - 1 DP - 1997 Jan TI - Asymptomatic lymphoma associated with elevation of immunoglobulin E. PG - 27-8 AB - BACKGROUND: Elevation of immunoglobulin E (IgE) is rarely detected in patients with underlying malignancy. There has been only one report of such a finding in a patient with a T cell lymphoma and none to our knowledge in association with a B-cell lymphoma. OBJECTIVE: To report a patient with elevation of IgE associated with a B-cell lineage lymphoma. MATERIAL AND METHODS: Case report and review of literature. RESULTS: A 73-year-old woman was found to have elevated IgE (11,766 IU/mL) in a routine evaluation for rhinitis. No underlying allergic diathesis or disease associated with IgE elevation was noted. Because of an abnormal lymphocyte profile, an extensive malignancy evaluation was performed which revealed a B-cell lymphoma. CONCLUSION: B-cell lineage lymphoma can be associated with elevated of IgE and should be included in the differential diagnosis in a patient presenting with this finding. FAU - Koutsonikolis, A AU - Koutsonikolis A AD - Department of Pediatrics, University of South Florida/All Children's Hospital, St. Petersburg, USA. FAU - Day, N AU - Day N FAU - Chamizo, W AU - Chamizo W FAU - Good, R A AU - Good RA FAU - Kornfeld, S J AU - Kornfeld SJ LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Ann Allergy Asthma Immunol JT - Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology JID - 9503580 RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Aged MH - Female MH - Humans MH - Hypergammaglobulinemia/*immunology/*pathology MH - Immunoglobulin E/*blood/*immunology MH - Lymphoma, B-Cell/*diagnosis/immunology/*pathology EDAT- 1997/01/01 00:00 MHDA- 1997/01/01 00:01 CRDT- 1997/01/01 00:00 PHST- 1997/01/01 00:00 [pubmed] PHST- 1997/01/01 00:01 [medline] PHST- 1997/01/01 00:00 [entrez] AID - S1081-1206(10)63366-2 [pii] AID - 10.1016/S1081-1206(10)63366-2 [doi] PST - ppublish SO - Ann Allergy Asthma Immunol. 1997 Jan;78(1):27-8. doi: 10.1016/S1081-1206(10)63366-2.