PMID- 9015143 OWN - NLM STAT- MEDLINE DCOM- 19970227 LR - 20190702 IS - 0027-5107 (Print) IS - 0027-5107 (Linking) VI - 372 IP - 2 DP - 1996 Dec TI - Mechanisms of induction of chromosomal aberrations and their detection by fluorescence in situ hybridization. PG - 247-58 AB - Fluorescence in situ hybridization (FISH) technique using chromosome specific probes has revolutionized the field of radiation cytogenetics in the last few years. Some of the new insights on the origins of radiation induced chromosome aberrations in human, mouse and Chinese hamster, using FISH are reviewed in this paper. FAU - Natarajan, A T AU - Natarajan AT AD - MGC Department of Radiation Genetics and Chemical Mutagenesis, Leiden University, The Netherlands. FAU - Balajee, A S AU - Balajee AS FAU - Boei, J J AU - Boei JJ FAU - Darroudi, F AU - Darroudi F FAU - Dominguez, I AU - Dominguez I FAU - Hande, M P AU - Hande MP FAU - Meijers, M AU - Meijers M FAU - Slijepcevic, P AU - Slijepcevic P FAU - Vermeulen, S AU - Vermeulen S FAU - Xiao, Y AU - Xiao Y LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Netherlands TA - Mutat Res JT - Mutation research JID - 0400763 RN - 0 (DNA Probes) RN - FA2DM6879K (Vidarabine) SB - IM MH - Animals MH - CHO Cells MH - *Chromosome Aberrations MH - Chromosomes/*radiation effects MH - Cricetinae MH - Cricetulus MH - DNA Probes MH - DNA Repair MH - Fibroblasts MH - G1 Phase MH - Humans MH - In Situ Hybridization, Fluorescence/*methods MH - Lymphocytes MH - Mice MH - Resting Phase, Cell Cycle MH - Spleen/cytology MH - Vidarabine/pharmacology EDAT- 1996/12/01 00:00 MHDA- 1996/12/01 00:01 CRDT- 1996/12/01 00:00 PHST- 1996/12/01 00:00 [pubmed] PHST- 1996/12/01 00:01 [medline] PHST- 1996/12/01 00:00 [entrez] AID - S0027510796001443 [pii] AID - 10.1016/s0027-5107(96)00144-3 [doi] PST - ppublish SO - Mutat Res. 1996 Dec;372(2):247-58. doi: 10.1016/s0027-5107(96)00144-3.