PMID- 9034629
OWN - NLM
STAT- MEDLINE
DCOM- 19970320
LR  - 20191101
IS  - 0742-2091 (Print)
IS  - 0742-2091 (Linking)
VI  - 12
IP  - 4-6
DP  - 1996 Dec
TI  - Vascular endothelial cells: targets for studying the activity of hair follicle 
      cell-produced VEGF.
PG  - 331-4
AB  - Fetal bovine aortic endothelial cells (FBAEC) were exposed to purified fractions 
      of conditioned medium from cultures of hair dermal papilla cells (DPC) to 
      determine the existence of any vascular endothelial growth factor (VEGF)-like 
      paracrine activity of the latter. Such fractions were tested for stimulation of 
      growth and migration of cultured FBAEC. In addition, VEGF secretion by DPC was 
      measured by radioassay of VEGF receptors using FBAEC as target cells. The results 
      showed that stimulation of FBAEC proliferation and migration following exposure 
      to purified conditioned medium was dose-dependent. Radioreceptor assays of 
      recombinant VEGF and purified DPC-conditioned medium showed competitive VEGF 
      binding in FBAEC.
FAU - Lachgar, S
AU  - Lachgar S
AD  - Laboratoire Culture de Peau, C.H.U. Rangueil, Toulouse, France.
FAU - Charveron, M
AU  - Charveron M
FAU - Gall, Y
AU  - Gall Y
FAU - Plouet, J
AU  - Plouet J
FAU - Bonafe, J L
AU  - Bonafe JL
LA  - eng
PT  - Journal Article
PL  - Switzerland
TA  - Cell Biol Toxicol
JT  - Cell biology and toxicology
JID - 8506639
RN  - 0 (Endothelial Growth Factors)
RN  - 0 (Lymphokines)
RN  - 0 (Vascular Endothelial Growth Factor A)
RN  - 0 (Vascular Endothelial Growth Factors)
SB  - IM
MH  - Animals
MH  - Aorta/cytology
MH  - Cattle
MH  - Cells, Cultured
MH  - Endothelial Growth Factors/*biosynthesis/*physiology
MH  - Endothelium, Vascular/*cytology/*drug effects
MH  - Fetus
MH  - Hair Follicle/cytology/*metabolism
MH  - Lymphokines/*biosynthesis/*physiology
MH  - Rats
MH  - Rats, Wistar
MH  - Vascular Endothelial Growth Factor A
MH  - Vascular Endothelial Growth Factors
EDAT- 1996/12/01 00:00
MHDA- 1996/12/01 00:01
CRDT- 1996/12/01 00:00
PHST- 1996/12/01 00:00 [pubmed]
PHST- 1996/12/01 00:01 [medline]
PHST- 1996/12/01 00:00 [entrez]
AID - 10.1007/BF00438166 [doi]
PST - ppublish
SO  - Cell Biol Toxicol. 1996 Dec;12(4-6):331-4. doi: 10.1007/BF00438166.