PMID- 9037411
OWN - NLM
STAT- MEDLINE
DCOM- 19970429
LR  - 20190614
IS  - 0006-8993 (Print)
IS  - 0006-8993 (Linking)
VI  - 745
IP  - 1-2
DP  - 1997 Jan 16
TI  - Comparisons of the effects of enterostatin on food intake and gastric emptying in 
      rats.
PG  - 205-9
AB  - The effects of central and peripheral administration of enterostatin (ENT) on 
      food intake and gastric emptying of a non-nutrient liquid meal have been studied 
      in rats. Intraperitoneal and intragastric administration of ENT at a dose of 120 
      nmol suppressed the intake of a high-fat diet but failed to inhibit gastric 
      emptying in Sprague-Dawley (SD) rats. Intracerebroventricular (i.c.v.) ENT (1 
      nmol) reduced intake of a high-fate diet in Osborne-Mendel (OM) and SD rats but 
      not in S5B/Pl rats, whereas it decreased gastric emptying in S5B/P1 and SD rats 
      but not in OM rats. The data suggest that although central ENT may reduce gastric 
      emptying rate, this effect is not related to the inhibitory effect of ENT on food 
      intake.
FAU - Lin, L
AU  - Lin L
AD  - Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
FAU - York, D A
AU  - York DA
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Netherlands
TA  - Brain Res
JT  - Brain research
JID - 0045503
RN  - 0 (Colipases)
RN  - 0 (Enzyme Precursors)
RN  - 0 (Protein Precursors)
RN  - 72994-53-7 (procolipase)
SB  - IM
MH  - Animals
MH  - Colipases/*pharmacology
MH  - Diet
MH  - Eating/*drug effects
MH  - Enzyme Precursors
MH  - Gastric Emptying/*drug effects
MH  - Injections
MH  - Injections, Intraperitoneal
MH  - Injections, Intraventricular
MH  - Male
MH  - Protein Precursors/*pharmacology
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Rats, Sprague-Dawley
MH  - Stomach
EDAT- 1997/01/16 00:00
MHDA- 1997/01/16 00:01
CRDT- 1997/01/16 00:00
PHST- 1997/01/16 00:00 [pubmed]
PHST- 1997/01/16 00:01 [medline]
PHST- 1997/01/16 00:00 [entrez]
AID - S0006-8993(96)01152-3 [pii]
AID - 10.1016/s0006-8993(96)01152-3 [doi]
PST - ppublish
SO  - Brain Res. 1997 Jan 16;745(1-2):205-9. doi: 10.1016/s0006-8993(96)01152-3.