PMID- 9039171 OWN - NLM STAT- MEDLINE DCOM- 19970312 LR - 20221207 IS - 0190-9622 (Print) IS - 0190-9622 (Linking) VI - 36 IP - 2 Pt 1 DP - 1997 Feb TI - Annular erythema associated with lupus erythematosus/Sjogren's syndrome. PG - 214-8 AB - BACKGROUND: Annular-polycyclic and papulosquamous lesions are associated with subacute cutaneous lupus erythematosus (SCLE). In some Asian cases, annular erythema has been associated with Sjogren's syndrome (SS). However, the relation between the two is unclear. OBJECTIVE: Our purpose was to clarify the clinical manifestations and immunologic features of patients with annular erythema. METHODS: This study included 15 patients with annular erythema. Systemic, serologic, and genetic findings were analyzed. RESULTS: Histologic examination showed perivascular and periappendageal lymphocytic infiltrates in all patients. However, LE-specific epidermal changes were observed in only three (20%). Although all patients at least partially demonstrated features of LE or SS, eight (53%) fulfilled the American Rheumatism Association criteria for systemic LE (SLE) and five (33%) were diagnosed with SS. Renal (20%) and central nervous system (7%) involvement was observed. Anti-Ro(SS-A) and anti-La(SS-B) antibodies were detected in nine (60%) and seven (47%) patients, respectively. There were no histocompatibility antigen (HLA) haplotype differences. CONCLUSION: Annular erythema in Asian patients is the counterpart of subacute skin lesions of LE in whites, except for the paucity of LE-specific histopathologic findings and HLA-DR3 tissue type. FAU - Watanabe, T AU - Watanabe T AD - Department of Dermatology, Faculty of Medicine, University of Tokyo, Japan. FAU - Tsuchida, T AU - Tsuchida T FAU - Ito, Y AU - Ito Y FAU - Kanda, N AU - Kanda N FAU - Ueda, Y AU - Ueda Y FAU - Tamaki, K AU - Tamaki K LA - eng PT - Comparative Study PT - Journal Article PL - United States TA - J Am Acad Dermatol JT - Journal of the American Academy of Dermatology JID - 7907132 RN - 0 (HLA Antigens) SB - IM MH - Adolescent MH - Adult MH - Asian People MH - Diagnosis, Differential MH - Erythema/*etiology MH - Female MH - Follow-Up Studies MH - HLA Antigens/analysis MH - Humans MH - Japan MH - Lupus Erythematosus, Cutaneous/*diagnosis/ethnology/immunology MH - Male MH - Middle Aged MH - Sjogren's Syndrome/*diagnosis MH - White People EDAT- 1997/02/01 00:00 MHDA- 1997/02/01 00:01 CRDT- 1997/02/01 00:00 PHST- 1997/02/01 00:00 [pubmed] PHST- 1997/02/01 00:01 [medline] PHST- 1997/02/01 00:00 [entrez] AID - S0190-9622(97)70283-4 [pii] AID - 10.1016/s0190-9622(97)70283-4 [doi] PST - ppublish SO - J Am Acad Dermatol. 1997 Feb;36(2 Pt 1):214-8. doi: 10.1016/s0190-9622(97)70283-4.