PMID- 9041462
OWN - NLM
STAT- MEDLINE
DCOM- 19970528
LR  - 20191101
IS  - 1067-5582 (Print)
IS  - 1067-5582 (Linking)
VI  - 19
IP  - 6
DP  - 1996 Nov
TI  - HLA class I antigens in Japanese patients with melanoma.
PG  - 428-32
AB  - In this study, we analyzed the frequencies of human leukocyte antigen (HLA) class 
      I alleles in 110 Japanese patients with melanoma using serological methods, and 
      compared such frequencies with clinical parameters. As expected, frequencies of 
      HLA allele distribution in patients with melanoma reflected the frequencies 
      observed in the normal Japanese population. Because these are different from 
      populations belonging to other races (e.g., white), it followed that the HLA 
      allele distribution in melanoma patients varies among different races. This 
      differences may have significant implications for T-cell-mediated, HLA-restricted 
      therapeutic modalities. No significant associations between HLA and clinical 
      parameters were noted in this study. This report may help design future clinical 
      trials involving therapeutic approaches based on HLA-restricted mechanisms.
FAU - Kageshita, T
AU  - Kageshita T
AD  - Department of Dermatology, Kumamoto University School of Medicine, Japan.
FAU - Naruse, T
AU  - Naruse T
FAU - Hirai, S
AU  - Hirai S
FAU - Horikoshi, T
AU  - Horikoshi T
FAU - Nakagawa, H
AU  - Nakagawa H
FAU - Tamaki, K
AU  - Tamaki K
FAU - Hayashibe, K
AU  - Hayashibe K
FAU - Ichihashi, M
AU  - Ichihashi M
FAU - Nakayama, J
AU  - Nakayama J
FAU - Hori, Y
AU  - Hori Y
FAU - Ozawa, A
AU  - Ozawa A
FAU - Miyahara, M
AU  - Miyahara M
FAU - Ohkido, M
AU  - Ohkido M
FAU - Inoko, H
AU  - Inoko H
FAU - Ono, T
AU  - Ono T
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Immunother Emphasis Tumor Immunol
JT  - Journal of immunotherapy with emphasis on tumor immunology : official journal of 
      the Society for Biological Therapy
JID - 9418950
RN  - 0 (HLA Antigens)
RN  - 0 (Histocompatibility Antigens Class I)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Alleles
MH  - Female
MH  - Gene Frequency
MH  - HLA Antigens/genetics/*immunology
MH  - Histocompatibility Antigens Class I/genetics/*immunology
MH  - Humans
MH  - Japan/epidemiology
MH  - Male
MH  - Melanoma/epidemiology/genetics/*immunology
MH  - Middle Aged
MH  - Polymorphism, Genetic
MH  - Skin Neoplasms/epidemiology/genetics/*immunology
EDAT- 1996/11/01 00:00
MHDA- 1996/11/01 00:01
CRDT- 1996/11/01 00:00
PHST- 1996/11/01 00:00 [pubmed]
PHST- 1996/11/01 00:01 [medline]
PHST- 1996/11/01 00:00 [entrez]
AID - 10.1097/00002371-199611000-00007 [doi]
PST - ppublish
SO  - J Immunother Emphasis Tumor Immunol. 1996 Nov;19(6):428-32. doi: 
      10.1097/00002371-199611000-00007.