PMID- 9042554
OWN - NLM
STAT- MEDLINE
DCOM- 19970430
LR  - 20181113
IS  - 0012-6667 (Print)
IS  - 0012-6667 (Linking)
VI  - 52 Suppl 7
DP  - 1996
TI  - Unresolved issues in the prevention of venous thromboembolism.
PG  - 1-6; discussion 6-7
AB  - Venous thromboembolism is a potentially fatal complication of surgery. The use of 
      graded pressure stockings in combination with unfractionated heparin (UFH) or a 
      low molecular weight heparin (LMWH) appears to be the safest and most effective 
      method of prevention. With some LMWHs, the risk of venous thromboembolism appears 
      to be lower than that associated with the use of standard UFH. A comparison of 
      heparin given before versus after surgery (with all patients receiving graded 
      pressure stockings) is justified. More information on the benefit-risk ratio of 
      minidose warfarin is also required. The risk of pulmonary embolism (PE) following 
      discharge from hospital after general surgery is relatively low and the extended 
      use of heparin may not be justified. The value of graded pressure stockings and 
      minidose warfarin for the prevention of PE should be determined. The risk of late 
      PE after orthopaedic surgery is unknown and also needs to be determined.
FAU - Baglin, T
AU  - Baglin T
AD  - Department of Clinical Haematology, Addenbrooke's NHS Trust, Cambridge, England.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Review
PL  - New Zealand
TA  - Drugs
JT  - Drugs
JID - 7600076
RN  - 0 (Anticoagulants)
RN  - 0 (Heparin, Low-Molecular-Weight)
RN  - 9005-49-6 (Heparin)
SB  - IM
MH  - Anticoagulants/*administration & dosage
MH  - Gravity Suits
MH  - Heparin/*administration & dosage
MH  - Heparin, Low-Molecular-Weight/*administration & dosage
MH  - Humans
MH  - Postoperative Complications/*prevention & control
MH  - Thromboembolism/*prevention & control
RF  - 30
EDAT- 1996/01/01 00:00
MHDA- 1996/01/01 00:01
CRDT- 1996/01/01 00:00
PHST- 1996/01/01 00:00 [pubmed]
PHST- 1996/01/01 00:01 [medline]
PHST- 1996/01/01 00:00 [entrez]
AID - 10.2165/00003495-199600527-00003 [doi]
PST - ppublish
SO  - Drugs. 1996;52 Suppl 7:1-6; discussion 6-7. doi: 
      10.2165/00003495-199600527-00003.