PMID- 9063365
OWN - NLM
STAT- MEDLINE
DCOM- 19970328
LR  - 20190516
IS  - 0002-9637 (Print)
IS  - 0002-9637 (Linking)
VI  - 56
IP  - 1
DP  - 1997 Jan
TI  - Correlation between human T cell lymphotropic virus type-1 and Strongyloides 
      stercoralis infections and serum immunoglobulin E responses in residents of 
      Okinawa, Japan.
PG  - 71-5
AB  - To clarify the relationship between Strongyloides stercoralis, infection with 
      human T cell lymphotropic virus type-1 (HTLV-1), and serum immunoglobulin E (IgE) 
      levels, epidemiologic investigations of these two infections were conducted in 
      inhabitants of Okinawa, a subtropical zone in Japan. Blood and feces samples were 
      taken from 1,347 healthy inhabitants (554 males and 793 females). Antibody to 
      HTLV-1 was measured by particle agglutination, enzyme-linked immunosorbent assay, 
      and Western blotting. The presence of Strongyloides was determined by direct 
      detection of rhabditiform larvae in fresh stool on agar-plate cultures. Serum IgE 
      levels in 127 inhabitants were measured by a fluoroenzyme immunoassay. Antibody 
      to HTLV-1 was detected in 23.0% of the blood samples and was more frequent in 
      females (25.1%) than in males (20.0%) (P < 0.05). Strongyloides were detected in 
      21.9% of the feces samples and were more frequent in males (31.9%) than in 
      females (14.9%) (P < 0.001). The prevalence of both infections increased with 
      age, especially in persons 50 years of age and older: The prevalence of 
      Strongyloides infection was significantly higher in HTLV-1 carriers (31.6%) than 
      in those without HTLV-1 infection (P < 0.001). The level of IgE was low in HTLV-1 
      carriers, and significantly lower in HTLV-1 carriers than in noncarriers among 
      inhabitants with Strongyloides infection. Both HTLV-1 and Strongyloides 
      infections are endemic in the area studied.
FAU - Hayashi, J
AU  - Hayashi J
AD  - Department of General Medicine, Kyushu University Hospital, Fukuoka, Japan.
FAU - Kishihara, Y
AU  - Kishihara Y
FAU - Yoshimura, E
AU  - Yoshimura E
FAU - Furusyo, N
AU  - Furusyo N
FAU - Yamaji, K
AU  - Yamaji K
FAU - Kawakami, Y
AU  - Kawakami Y
FAU - Murakami, H
AU  - Murakami H
FAU - Kashiwagi, S
AU  - Kashiwagi S
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Trop Med Hyg
JT  - The American journal of tropical medicine and hygiene
JID - 0370507
RN  - 0 (Antibodies, Helminth)
RN  - 0 (HTLV-I Antibodies)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adult
MH  - Age Distribution
MH  - Aged
MH  - Aged, 80 and over
MH  - Agglutination Tests
MH  - Agricultural Workers' Diseases/epidemiology/immunology
MH  - Animals
MH  - Antibodies, Helminth/blood
MH  - Blotting, Western
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Female
MH  - HTLV-I Antibodies/blood
MH  - HTLV-I Infections/complications/epidemiology/*immunology
MH  - Humans
MH  - Immunoglobulin E/*blood
MH  - Japan/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Sex Distribution
MH  - Strongyloides stercoralis/*immunology
MH  - Strongyloidiasis/complications/epidemiology/*immunology
EDAT- 1997/01/01 00:00
MHDA- 1997/01/01 00:01
CRDT- 1997/01/01 00:00
PHST- 1997/01/01 00:00 [pubmed]
PHST- 1997/01/01 00:01 [medline]
PHST- 1997/01/01 00:00 [entrez]
AID - 10.4269/ajtmh.1997.56.71 [doi]
PST - ppublish
SO  - Am J Trop Med Hyg. 1997 Jan;56(1):71-5. doi: 10.4269/ajtmh.1997.56.71.