PMID- 9068892
OWN - NLM
STAT- MEDLINE
DCOM- 19970616
LR  - 20190815
IS  - 0142-9612 (Print)
IS  - 0142-9612 (Linking)
VI  - 18
IP  - 4
DP  - 1997 Feb
TI  - Investigation of the dissolution of the bioceramic hydroxyapatite in the presence 
      of titanium ions using ToF-SIMS and XPS.
PG  - 311-6
AB  - Time-of-flight secondary ion mass spectrometry (ToF-SIMS) and X-ray photoelectron 
      spectroscopy (XPS) analyses have been used to investigate the dissolution of 
      hydroxyapatite in the presence of titanium chloride suggesting the substitution 
      of titanium ions for calcium in the hydroxyapatite structure. The surface 
      analytical data suggest that titanium was incorporated within the solid phase as 
      titanium phosphate. Comparison of relative ion intensities in the ToF-SIMS 
      spectra reveals changes in the composition of the surface chemistry of 
      hydroxyapatite. These relative ion intensities show that the maximum surface 
      uptake of titanium occurred at a solution concentration of 500 ppm titanium 
      chloride for a time of incubation of 30 min. These data correlate with that 
      obtained using XPS highlighting the semi-quantitative information which ToF-SIMS 
      can provide.
FAU - Leadley, S R
AU  - Leadley SR
AD  - Department of Pharmaceutical Sciences, University of Nottingham, UK.
FAU - Davies, M C
AU  - Davies MC
FAU - Ribeiro, C C
AU  - Ribeiro CC
FAU - Barbosa, M A
AU  - Barbosa MA
FAU - Paul, A J
AU  - Paul AJ
FAU - Watts, J F
AU  - Watts JF
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Biomaterials
JT  - Biomaterials
JID - 8100316
RN  - 0 (Biocompatible Materials)
RN  - 0 (Cations)
RN  - 91D9GV0Z28 (Durapatite)
RN  - D1JT611TNE (Titanium)
SB  - IM
MH  - Biocompatible Materials/*chemistry
MH  - Cations
MH  - Ceramics/*chemistry
MH  - Durapatite/*chemistry
MH  - Spectrometry, Mass, Secondary Ion
MH  - Spectrometry, X-Ray Emission
MH  - Titanium/*chemistry
EDAT- 1997/02/01 00:00
MHDA- 1997/02/01 00:01
CRDT- 1997/02/01 00:00
PHST- 1997/02/01 00:00 [pubmed]
PHST- 1997/02/01 00:01 [medline]
PHST- 1997/02/01 00:00 [entrez]
AID - S0142961296001342 [pii]
AID - 10.1016/s0142-9612(96)00134-2 [doi]
PST - ppublish
SO  - Biomaterials. 1997 Feb;18(4):311-6. doi: 10.1016/s0142-9612(96)00134-2.