PMID- 9069320
OWN - NLM
STAT- MEDLINE
DCOM- 19970331
LR  - 20190708
IS  - 0360-3016 (Print)
IS  - 0360-3016 (Linking)
VI  - 37
IP  - 2
DP  - 1997 Jan 15
TI  - Consistency of three-dimensional planning target volumes across physicians and 
      institutions.
PG  - 445-53
AB  - PURPOSE: Three-dimensional treatment planning depends upon exact and consistent 
      delineation of target volumes. This study tested whether different physicians 
      from different institutions vary significantly in their creation of planning 
      target volumes (PTVs). METHODS AND MATERIALS: Eight physicians from three 
      different institutions created partial planning target volumes for nine clinical 
      test cases. Their target volumes were evaluated qualitatively and quantitatively. 
      Quantitative results were tested for significant differences. RESULTS: 
      Qualitative analysis showed the physicians to vary in (a) the margin placed 
      around the clinical target volume, (b) the margin used near critical structures, 
      and (c) handling of concavities in the clinical target volume. Quantitative 
      analysis showed these variations to result in statistically significant 
      differences in the measured volume of the physicians' planning target volumes. 
      CONCLUSIONS: Individual physicians and institutions differ significantly in their 
      creation of planning target volumes, suggesting individual and institutional 
      differences in the working definition for the PTV. Implications of this fact are 
      discussed, along with areas where standardization can be improved.
FAU - Ketting, C H
AU  - Ketting CH
AD  - Department of Radiation Medicine, Loma Linda University Medical Center, CA, USA.
FAU - Austin-Seymour, M
AU  - Austin-Seymour M
FAU - Kalet, I
AU  - Kalet I
FAU - Unger, J
AU  - Unger J
FAU - Hummel, S
AU  - Hummel S
FAU - Jacky, J
AU  - Jacky J
LA  - eng
GR  - LM04174-08/LM/NLM NIH HHS/United States
GR  - N01-CM97566/CM/NCI NIH HHS/United States
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Int J Radiat Oncol Biol Phys
JT  - International journal of radiation oncology, biology, physics
JID - 7603616
SB  - IM
MH  - Analysis of Variance
MH  - Humans
MH  - Radiation Oncology/*standards
MH  - Radiotherapy Dosage
MH  - Radiotherapy Planning, Computer-Assisted/*standards
EDAT- 1997/01/15 00:00
MHDA- 1997/01/15 00:01
CRDT- 1997/01/15 00:00
PHST- 1997/01/15 00:00 [pubmed]
PHST- 1997/01/15 00:01 [medline]
PHST- 1997/01/15 00:00 [entrez]
AID - S0360301696004592 [pii]
AID - 10.1016/s0360-3016(96)00459-2 [doi]
PST - ppublish
SO  - Int J Radiat Oncol Biol Phys. 1997 Jan 15;37(2):445-53. doi: 
      10.1016/s0360-3016(96)00459-2.