PMID- 9091671 OWN - NLM STAT- MEDLINE DCOM- 19970404 LR - 20161017 IS - 0098-7484 (Print) IS - 0098-7484 (Linking) VI - 277 IP - 12 DP - 1997 Mar 26 TI - Relationship between HLA-C locus and restenosis after coronary artery balloon angioplasty. PG - 983-4 AB - OBJECTIVES: To determine the relationship between human leukocyte antigen (HLA) loci and restenosis after percutaneous transluminal coronary angioplasty (PTCA). DESIGN AND SETTING: Cross-sectional study in patients treated by PTCA at Juntendo University Hospital, Tokyo, Japan. PATIENTS: A total of 65 patients (58 males and 7 females) with coronary artery stenosis who were consecutively selected between October 1994 and June 1995. MAIN OUTCOME MEASURES: Significant relationships between the restenosis and the HLA-Cw1. RESULTS: Among HLA-C locus, Cw1 was negatively related to restenosis (multivariate adjusted odds ratio, 0.19; 95% confidence interval, 0.06-0.63; P=.007). CONCLUSIONS: In HLA typing, Cw1 may be a useful marker for the prediction of restenosis after PTCA. FAU - Watanabe, Y AU - Watanabe Y AD - Department of Cardiology, Juntendo University, Japan. FAU - Yamada, N AU - Yamada N FAU - Yokoi, H AU - Yokoi H FAU - Fujiwara, Y AU - Fujiwara Y FAU - Mokuno, H AU - Mokuno H FAU - Daida, H AU - Daida H FAU - Yamaguchi, H AU - Yamaguchi H LA - eng PT - Journal Article PL - United States TA - JAMA JT - JAMA JID - 7501160 RN - 0 (Biomarkers) RN - 0 (HLA-C Antigens) RN - 0 (HLA-Cw1 antigen) SB - IM MH - Aged MH - *Angioplasty, Balloon, Coronary MH - Biomarkers MH - Coronary Disease/*genetics/immunology/*therapy MH - Cross-Sectional Studies MH - Female MH - HLA-C Antigens/*genetics MH - Humans MH - Logistic Models MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Phenotype MH - Recurrence EDAT- 1997/03/26 00:00 MHDA- 1997/03/26 00:01 CRDT- 1997/03/26 00:00 PHST- 1997/03/26 00:00 [pubmed] PHST- 1997/03/26 00:01 [medline] PHST- 1997/03/26 00:00 [entrez] PST - ppublish SO - JAMA. 1997 Mar 26;277(12):983-4.