PMID- 9105438 OWN - NLM STAT- MEDLINE DCOM- 19970703 LR - 20190716 IS - 0001-6489 (Print) IS - 0001-6489 (Linking) VI - 117 IP - 2 DP - 1997 Mar TI - Profound permanent hearing impairment in childhood: causative factors in two European countries. PG - 158-60 AB - A collaboration between Denmark and Wales was established in order to evaluate any differences between countries in factors causing permanent childhood hearing impairment (PCHI). Two identical 6-year birth-cohorts from 1975-1980 suffering from a permanent hearing loss > or = 90 dB HL in the better hearing ear, averaged across 0.5-4 kHz (BEHL), were included in the analysis. The overall estimated prevalence of children with this loss was 0.41/live births in Wales (n = 59). In Denmark the overall prevalence was 0.45/1,000 live births (n = 34), there being no significant differences in prevalence between the two countries. Both cohorts were subjected to a multidisciplinary investigation protocol. No significant differences were found between countries in the proportion of hearing impairment caused by the various factors, when based on uniform criteria and identical birth-cohorts. The proportion of inherited hearing loss is 47-50% in the two countries. Within inheritance the proportion of non-syndromal/syndromal inheritance differs slightly, as non-syndromal inheritance comprises 50% in Wales, and 76% in Denmark. The reported proportion of 16-34% of unknown factors causing profound PCHI emphasises the need for appropriate protocols for aetiological evaluation. FAU - Parving, A AU - Parving A AD - Audiological Department, Bispebjerg Hospital H:S, Copenhagen, Denmark. bbhaudap@login.dknct.dk FAU - Stephens, D AU - Stephens D LA - eng PT - Journal Article PL - England TA - Acta Otolaryngol JT - Acta oto-laryngologica JID - 0370354 SB - IM MH - Child MH - Cohort Studies MH - Deafness/epidemiology/*etiology MH - Denmark/epidemiology MH - Humans MH - Prevalence MH - Wales/epidemiology EDAT- 1997/03/01 00:00 MHDA- 1997/03/01 00:01 CRDT- 1997/03/01 00:00 PHST- 1997/03/01 00:00 [pubmed] PHST- 1997/03/01 00:01 [medline] PHST- 1997/03/01 00:00 [entrez] AID - 10.3109/00016489709117759 [doi] PST - ppublish SO - Acta Otolaryngol. 1997 Mar;117(2):158-60. doi: 10.3109/00016489709117759.