PMID- 9106020
OWN - NLM
STAT- MEDLINE
DCOM- 19970702
LR  - 20181130
IS  - 1120-009X (Print)
IS  - 1120-009X (Linking)
VI  - 9
IP  - 1
DP  - 1997 Feb
TI  - Cis/carboplatin + vinorelbine +/- radiotherapy in stage III and IV non small cell 
      lung carcinoma.
PG  - 62-5
AB  - The aim of this study was the retrospective evaluation of the effectiveness of 
      cis/carboplatin + vinorelbine +/- radiotherapy in 118 patients with advanced non 
      small cell lung carcinoma (NSCLC). To evaluate the response, pts were divided 
      into three groups: a) Stage III pts. who received both chemotherapy and 
      radiotherapy treatment (RC + RP = 43.75%, median survival 16.25 months); b) Stage 
      III pts. who underwent only CT because RT was contraindicated (RC + RP = 21.95%, 
      median survival 12.7 months); c) Stage II pts treated with CT alone (RC + RP = 
      20%, median survival = 12.1 months). Toxicity was mild. The results of the 
      present study, both in terms of response rate and survival, confirm the 
      effectiveness of the combination cis/carboplatin + vinorelbine +/- radiotherapy 
      as palliative treatment of advanced NSCLC.
FAU - Tomirotti, M
AU  - Tomirotti M
AD  - Oncology and Chemotherapy Dept., Fatebenefratelli and Oftalmico Hospital, Milan, 
      Italy.
FAU - Galassi, B
AU  - Galassi B
FAU - Dambrosio, M
AU  - Dambrosio M
FAU - Fossati, V
AU  - Fossati V
FAU - Gramegna, G
AU  - Gramegna G
FAU - Colombo, F
AU  - Colombo F
FAU - Rovej, R
AU  - Rovej R
FAU - Scanni, A
AU  - Scanni A
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Chemother
JT  - Journal of chemotherapy (Florence, Italy)
JID - 8907348
RN  - 5V9KLZ54CY (Vinblastine)
RN  - BG3F62OND5 (Carboplatin)
RN  - Q20Q21Q62J (Cisplatin)
RN  - Q6C979R91Y (Vinorelbine)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Antineoplastic Combined Chemotherapy Protocols/adverse effects/*therapeutic use
MH  - Carboplatin/administration & dosage
MH  - Carcinoma, Non-Small-Cell Lung/drug therapy/radiotherapy/*therapy
MH  - Cisplatin/administration & dosage
MH  - Combined Modality Therapy
MH  - Female
MH  - Humans
MH  - Lung Neoplasms/drug therapy/radiotherapy/*therapy
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Retrospective Studies
MH  - Vinblastine/administration & dosage/analogs & derivatives
MH  - Vinorelbine
EDAT- 1997/02/01 00:00
MHDA- 1997/02/01 00:01
CRDT- 1997/02/01 00:00
PHST- 1997/02/01 00:00 [pubmed]
PHST- 1997/02/01 00:01 [medline]
PHST- 1997/02/01 00:00 [entrez]
AID - 10.1179/joc.1997.9.1.62 [doi]
PST - ppublish
SO  - J Chemother. 1997 Feb;9(1):62-5. doi: 10.1179/joc.1997.9.1.62.