PMID- 9109930
OWN - NLM
STAT- MEDLINE
DCOM- 19970501
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 94
IP  - 2
DP  - 1997 Apr
TI  - Philadelphia chromosome in chronic myelogenous leukemia: confirmation of 
      cytogenetic diagnosis in Ph positive and negative cases by fluorescence in situ 
      hybridization.
PG  - 75-8
AB  - In this study, patients with Philadelphia (Ph) negative and positive chronic 
      myelogenous leukemia (CML) were analyzed by unicolor- and dual color- (DC) 
      fluorescence in situ hybridization (FISH) using abl and bcr cosmid probes. 
      Unicolor- and DC-FISH analysis revealed a BCR-ABL fusion in a Ph-negative 
      patient. DC-FISH to interphase nuclei revealed the BCR-ABL fusion, even though no 
      metaphases were available for metaphase-FISH and conventional cytogenetic 
      analysis. In the remaining cases, the findings of FISH were in agreement with the 
      cytogenetic results.
FAU - Acar, H
AU  - Acar H
AD  - Department of Medical Genetics, University of Selcuk, Konya, Turkey.
FAU - Stewart, J
AU  - Stewart J
FAU - Connor, M J
AU  - Connor MJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
RN  - 0 (DNA, Neoplasm)
RN  - EC 2.7.10.2 (Fusion Proteins, bcr-abl)
SB  - IM
MH  - DNA, Neoplasm/genetics
MH  - Fusion Proteins, bcr-abl/*genetics
MH  - Genes, abl
MH  - Humans
MH  - In Situ Hybridization, Fluorescence/methods
MH  - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis/*genetics
MH  - Translocation, Genetic
EDAT- 1997/04/01 00:00
MHDA- 1997/04/01 00:01
CRDT- 1997/04/01 00:00
PHST- 1997/04/01 00:00 [pubmed]
PHST- 1997/04/01 00:01 [medline]
PHST- 1997/04/01 00:00 [entrez]
AID - S0165-4608(96)00167-7 [pii]
AID - 10.1016/s0165-4608(96)00167-7 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1997 Apr;94(2):75-8. doi: 10.1016/s0165-4608(96)00167-7.