PMID- 9122471
OWN - NLM
STAT- MEDLINE
DCOM- 19970418
LR  - 20161124
IS  - 0033-8362 (Print)
IS  - 0033-8362 (Linking)
VI  - 92
IP  - 6
DP  - 1996 Dec
TI  - [Left ventricular function in patients with chronic ischemic cardiopathy: 
      relationship with the status of myocardial perfusion].
PG  - 778-81
AB  - The aim of this study was the evaluation of left ventricular function compared to 
      myocardial perfusion in patients with chronic coronary artery disease (CAD). 
      Thirty-two patients with chronic CAD (27 men and 5 women, mean age 58 +/- 9 
      years) underwent radionuclide angiography and rest-redistribution thallium-201 
      (TI-201) single photon emission Computed Tomography (SPECT). Ejection fraction 
      (EF, %), peak filling rate (PFR, end diastolic volume/second), and the 
      coefficient of variation of the regional time to PFR (CV-TPFR, %) were computed. 
      Patients with severe irreversible defects (i.e. with TI-201 uptake < 50%) had 
      lower EF (42 +/- 7% vs 52 +/- 11%, p < 0.01) and lower PFR (1.9 +/- 0.4 vs 3.1 
      +/- 1.0, p < 0.0005) than those without. Patients with severe irreversible 
      perfusion defects in the left anterior descending artery territory had lower EF 
      (41 +/- 6% vs 50 +/- 11%, p < 0.01), lower PFR (1.8 +/- 0.3 vs 2.8 +/- 1.0, p < 
      0.005), and higher CV-TPFR (39 +/- 22 vs 13 +/- 7, p < 0.001) than those without. 
      The results of the present study indicate that in patients with chronic CAD left 
      ventricular systolic and diastolic function is more deteriorated when the left 
      anterior descending artery is involved. Similarly, the presence of severe 
      irreversible perfusion defects is clearly associated with significantly lower EF 
      and PFR.
FAU - Sullo, P
AU  - Sullo P
AD  - Cattedra di Medicina Nucleare, Centro per la Medicina Nucleare del CNR, 
      Universita Federico II, Napoli.
FAU - Franculli, F
AU  - Franculli F
FAU - Pace, L
AU  - Pace L
FAU - Perrone-Filardi, P
AU  - Perrone-Filardi P
FAU - Cuocolo, A
AU  - Cuocolo A
FAU - Soricelli, A
AU  - Soricelli A
FAU - Squame, F
AU  - Squame F
FAU - Betocchi, S
AU  - Betocchi S
FAU - Chiariello, M
AU  - Chiariello M
FAU - Salvatore, M
AU  - Salvatore M
LA  - ita
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
TT  - La funzione ventricolare sinistra nei pazienti con cardiopatia ischemica cronica: 
      relazione con lo stato perfusivo micardico.
PL  - Italy
TA  - Radiol Med
JT  - La Radiologia medica
JID - 0177625
SB  - IM
MH  - Adult
MH  - Aged
MH  - Chronic Disease
MH  - Coronary Circulation/*physiology
MH  - Female
MH  - *Gated Blood-Pool Imaging
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Ischemia/*diagnostic imaging/*physiopathology
MH  - *Tomography, Emission-Computed, Single-Photon
MH  - Ventricular Function, Left/*physiology
EDAT- 1996/12/01 00:00
MHDA- 1996/12/01 00:01
CRDT- 1996/12/01 00:00
PHST- 1996/12/01 00:00 [pubmed]
PHST- 1996/12/01 00:01 [medline]
PHST- 1996/12/01 00:00 [entrez]
PST - ppublish
SO  - Radiol Med. 1996 Dec;92(6):778-81.