PMID- 9135316 OWN - NLM STAT- MEDLINE DCOM- 19970515 LR - 20190515 IS - 0007-0912 (Print) IS - 0007-0912 (Linking) VI - 78 IP - 3 DP - 1997 Mar TI - Validation of thoracic electrical bioimpedance as a porcine research tool. PG - 323-5 AB - We have compared the accuracy of two methods of measuring cardiac output, thoracic electrical bioimpedance (TEB) and thermodilution (TD), in pigs. We studied four anaesthetized pigs, producing 145 paired cardiac output values over a range of TD cardiac outputs of 2.6-12.6 litre min-1. TEB cardiac output was less than that measured by TD, by a constant factor throughout the observed range of values, because of differences in porcine thoracic shape. The Pearson product moment correlation coefficient suggested a good correlation (r = 0.984, P < 0.001). More importantly, analysis by the Bland and Altman statistical method suggested a high level of agreement, with 95% confidence intervals of +/- 1.0 litre min-1. These results suggest that TEB can be used as a satisfactory method to measure cardiac output in porcine models. FAU - Broomhead, C J AU - Broomhead CJ AD - Department of Anaesthetics, University College London Hospitals, Middlesex Hospital. FAU - Wright, S J AU - Wright SJ FAU - Kiff, K M AU - Kiff KM FAU - Withington, P S AU - Withington PS LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Br J Anaesth JT - British journal of anaesthesia JID - 0372541 SB - IM MH - Animals MH - *Cardiac Output MH - *Cardiography, Impedance MH - Reproducibility of Results MH - Swine MH - Thermodilution EDAT- 1997/03/01 00:00 MHDA- 1997/03/01 00:01 CRDT- 1997/03/01 00:00 PHST- 1997/03/01 00:00 [pubmed] PHST- 1997/03/01 00:01 [medline] PHST- 1997/03/01 00:00 [entrez] AID - S0007-0912(17)41950-7 [pii] AID - 10.1093/bja/78.3.323 [doi] PST - ppublish SO - Br J Anaesth. 1997 Mar;78(3):323-5. doi: 10.1093/bja/78.3.323.