PMID- 9138241
OWN - NLM
STAT- MEDLINE
DCOM- 19970714
LR  - 20151119
IS  - 0587-2871 (Print)
IS  - 0587-2871 (Linking)
VI  - 33
IP  - 3
DP  - 1997 May-Jun
TI  - Efficacy of hyposensitization in feline allergic diseases based upon results of 
      in vitro testing for allergen-specific immunoglobulin E.
PG  - 282-8
AB  - A survey was undertaken to evaluate the responses to hyposensitization in cats 
      for which a diagnosis of allergic disease was made by assessment of clinical 
      signs and evaluation of allergen-specific immunoglobulin E (IgE) using the 
      radioallergosorbent test (RAST). Eighty-one cases were available for analysis. In 
      39 cases, a dietary change resulted in some subjective improvement, which usually 
      was minimal; however, some cases had significant improvement. In 75.3% of cases, 
      an improvement of at least 50% was noted and ascribed to a combination of 
      immunotherapy and dietary change, when implemented. The response of the 42 cases 
      in which immunotherapy alone was used or where there was no response to dietary 
      change was broadly similar. Response of the specific dermatological conditions 
      ranged from 93.6% in the case of linear granuloma to 60% in cases where 
      self-induced hair loss was evident. Response also was good in cases of presumed 
      allergic asthma (86.1% improvement) and suspected allergic otitis externa (62.6% 
      improvement). In nine patients, the hyposensitization was discontinued due to 
      lack of response. The results suggest that confirmation of a suspected diagnosis 
      of allergic disease in cats by means of in vitro tests and subsequent therapy 
      with hyposensitization should be a major consideration in feline practice.
FAU - Halliwell, R E
AU  - Halliwell RE
AD  - Department of Veterinary Clinical Studies, Royal (Dick) School of Veterinary 
      Studies, Edinburgh, Scotland.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Am Anim Hosp Assoc
JT  - Journal of the American Animal Hospital Association
JID - 0415027
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Animals
MH  - Cat Diseases/diagnosis/*immunology/*therapy
MH  - Cats
MH  - Desensitization, Immunologic/methods/standards/*veterinary
MH  - Diet Therapy/standards/veterinary
MH  - Food Hypersensitivity/immunology/therapy/veterinary
MH  - Hypersensitivity/immunology/therapy/*veterinary
MH  - Immunoglobulin E/*blood
MH  - In Vitro Techniques
MH  - Radioallergosorbent Test/methods/veterinary
MH  - Surveys and Questionnaires
MH  - Syndrome
MH  - Treatment Outcome
EDAT- 1997/05/01 00:00
MHDA- 1997/05/01 00:01
CRDT- 1997/05/01 00:00
PHST- 1997/05/01 00:00 [pubmed]
PHST- 1997/05/01 00:01 [medline]
PHST- 1997/05/01 00:00 [entrez]
AID - 10.5326/15473317-33-3-282 [doi]
PST - ppublish
SO  - J Am Anim Hosp Assoc. 1997 May-Jun;33(3):282-8. doi: 10.5326/15473317-33-3-282.