PMID- 9146073
OWN - NLM
STAT- MEDLINE
DCOM- 19970624
LR  - 20061115
IS  - 0009-918X (Print)
IS  - 0009-918X (Linking)
VI  - 37
IP  - 1
DP  - 1997 Jan
TI  - [Small hand muscle atrophy as an initial sign in HTLV-I associated myelopathy].
PG  - 44-6
AB  - A 68-year-old female had been well until the age of 52 when she noticed weakness 
      and atrophy of her right small hand muscles. She began to have gait disturbance 
      at the age of 63. On admission, neurological examinations revealed atrophy and 
      weakness of the small hand muscles on both sides as well as spastic paraparesis. 
      As the antibody titer for human T-lymphotropic virus type I (HTLV-I) was elevated 
      both in the serum and CSF, a diagnosis of HTLV-I associated myelopathy (HAM) was 
      made. Electrophysiological studies showed neurogenic changes and suggested 
      anterior horn cell involvement. After oral administration of prednisolone, her 
      spasticity and gait disturbance improved slightly. Small hand muscle atrophy can 
      be one of the initial signs of HAM, and may mimic amyotrophic lateral sclerosis 
      and cervical spondylosis.
FAU - Ishida, C
AU  - Ishida C
AD  - Department of Neurology, Ishikawa Prefectual Central Hospital.
FAU - Uchiyama, S
AU  - Uchiyama S
FAU - Matsubara, S
AU  - Matsubara S
LA  - jpn
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Rinsho Shinkeigaku
JT  - Rinsho shinkeigaku = Clinical neurology
JID - 0417466
SB  - IM
MH  - Aged
MH  - Female
MH  - *Hand
MH  - Humans
MH  - Muscular Atrophy/*etiology
MH  - Paraparesis, Tropical Spastic/*complications
EDAT- 1997/01/01 00:00
MHDA- 1997/01/01 00:01
CRDT- 1997/01/01 00:00
PHST- 1997/01/01 00:00 [pubmed]
PHST- 1997/01/01 00:01 [medline]
PHST- 1997/01/01 00:00 [entrez]
PST - ppublish
SO  - Rinsho Shinkeigaku. 1997 Jan;37(1):44-6.