PMID- 9159404 OWN - NLM STAT- MEDLINE DCOM- 19970725 LR - 20190822 IS - 0385-5600 (Print) IS - 0385-5600 (Linking) VI - 41 IP - 4 DP - 1997 TI - Breast milk is not a significant source for early Epstein-Barr virus or human herpesvirus 6 infection in infants: a seroepidemiologic study in 2 endemic areas of human T-cell lymphotropic virus type I in Japan. PG - 309-12 AB - In order to evaluate the possibility of Epstein-Barr virus (EBV) and human herpesvirus 6 (HHV-6) transmission via breast milk, a total of 331 serum specimens collected from bottle-fed and breast-fed children and their mothers, in 2 endemic areas of human T-cell lymphotropic virus type I (HTLV-I) in Japan, were assayed for antibodies to EBV and HHV-6. The seroprevalences of EBV and HHV-6 were over 95% both in the mothers of bottle-fed children and in those of breast-fed children. The seroprevalence of EBV at 12-23 months of age was 54.5% (36/66) and 55.8% (24/43) in breast-fed children and bottle-fed children, respectively. The seroprevalence of HHV-6 at 12-23 months of age was 90.9% (60/66) and 93.0% (40/43) in breast-fed children and bottle-fed children, respectively. No difference was observed between the seroprevalences of EBV and HHV-6 in breast-fed and bottle-fed children at 12-23 months of age. Our seroepidemiologic data indicate that breast milk is not a significant source of early EBV or HHV-6 infection in infancy. FAU - Kusuhara, K AU - Kusuhara K AD - Department of Pediatrics, Faculty of Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan. FAU - Takabayashi, A AU - Takabayashi A FAU - Ueda, K AU - Ueda K FAU - Hidaka, Y AU - Hidaka Y FAU - Minamishima, I AU - Minamishima I FAU - Take, H AU - Take H FAU - Fujioka, K AU - Fujioka K FAU - Imai, S AU - Imai S FAU - Osato, T AU - Osato T LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Australia TA - Microbiol Immunol JT - Microbiology and immunology JID - 7703966 RN - 0 (Antibodies, Viral) SB - IM MH - Antibodies, Viral/analysis MH - Female MH - HTLV-I Infections/epidemiology MH - Herpesviridae Infections/*epidemiology/*transmission MH - *Herpesvirus 4, Human MH - *Herpesvirus 6, Human MH - Humans MH - Infant MH - Infant, Newborn MH - Infectious Disease Transmission, Vertical MH - Japan/epidemiology MH - Milk, Human/*virology MH - Pregnancy MH - Prevalence MH - Seroepidemiologic Studies MH - Tumor Virus Infections/*epidemiology/*transmission EDAT- 1997/01/01 00:00 MHDA- 1997/01/01 00:01 CRDT- 1997/01/01 00:00 PHST- 1997/01/01 00:00 [pubmed] PHST- 1997/01/01 00:01 [medline] PHST- 1997/01/01 00:00 [entrez] AID - 10.1111/j.1348-0421.1997.tb01206.x [doi] PST - ppublish SO - Microbiol Immunol. 1997;41(4):309-12. doi: 10.1111/j.1348-0421.1997.tb01206.x.