PMID- 9166997
OWN - NLM
STAT- MEDLINE
DCOM- 19970814
LR  - 20061115
IS  - 0192-415X (Print)
IS  - 0192-415X (Linking)
VI  - 25
IP  - 1
DP  - 1997
TI  - Effects of Poncirus trifoliata on type I hypersensitivity reaction.
PG  - 51-6
AB  - A study was carried out to examine the effect of an aqueous extract from immature 
      fruit of Poncirus trifoliata L. (Rutaceae) (PTIFE) on the type I hypersensitivity 
      reaction. Forty-eight hour PCA (passive cutaneous anaphylaxis) in rats was 
      significantly inhibited by the oral administration of PTIFE (200 mg/kg). It also 
      inhibited histamine release from rat peritoneal mast cells (RPMC) induced by 
      mouse anti-dinitrophenyl (DNP)-IgE and dinitrophenyl-human serum albumin 
      (DNP-HSA). These results suggest that PTIFE has anti-allergic action against the 
      type I hypersensitivity reaction.
FAU - Lee, Y M
AU  - Lee YM
AD  - Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan, 
      Chonbuk, Republic of Korea.
FAU - Kim, C Y
AU  - Kim CY
FAU - Kim, Y C
AU  - Kim YC
FAU - Kim, H M
AU  - Kim HM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Singapore
TA  - Am J Chin Med
JT  - The American journal of Chinese medicine
JID - 7901431
RN  - 0 (Antibodies)
RN  - 0 (Antigens)
RN  - 0 (Dinitrophenols)
RN  - 0 (Fungicides, Industrial)
RN  - 0 (Plant Extracts)
RN  - 0 (Serum Albumin)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Administration, Oral
MH  - Animals
MH  - Antibodies/administration & dosage
MH  - Antigens/immunology/toxicity
MH  - Dinitrophenols/toxicity
MH  - Disease Models, Animal
MH  - Fruit/chemistry
MH  - Fungicides, Industrial/toxicity
MH  - Histamine Release/drug effects
MH  - Humans
MH  - Hypersensitivity, Immediate/*drug therapy
MH  - Immunoglobulin E/immunology
MH  - Injections, Intradermal
MH  - Male
MH  - Mast Cells/drug effects/metabolism
MH  - Mice
MH  - Passive Cutaneous Anaphylaxis/*drug effects
MH  - Peritoneum/cytology/drug effects
MH  - Plant Extracts/administration & dosage/pharmacology/*therapeutic use
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Serum Albumin/immunology
MH  - Specific Pathogen-Free Organisms
EDAT- 1997/01/01 00:00
MHDA- 1997/01/01 00:01
CRDT- 1997/01/01 00:00
PHST- 1997/01/01 00:00 [pubmed]
PHST- 1997/01/01 00:01 [medline]
PHST- 1997/01/01 00:00 [entrez]
AID - S0192415X97000081 [pii]
AID - 10.1142/S0192415X97000081 [doi]
PST - ppublish
SO  - Am J Chin Med. 1997;25(1):51-6. doi: 10.1142/S0192415X97000081.