PMID- 9176461
OWN - NLM
STAT- MEDLINE
DCOM- 19970626
LR  - 20190707
IS  - 0015-0282 (Print)
IS  - 0015-0282 (Linking)
VI  - 67
IP  - 6
DP  - 1997 Jun
TI  - Indisputable double paternity in dizygous twins.
PG  - 1159-61
AB  - OBJECTIVE: To report a case of heteropaternal superfecundation. DESIGN: Case 
      report. SETTING: University paternity laboratory. PATIENT(S): Father, mother, and 
      a set of twins. INTERVENTION(S): Blood typing conventional markers, as well as 
      polymerase chain reaction loci and restriction fragment length polymorphism loci 
      of DNA. MAIN OUTCOME MEASURE(S): Heteropaternal superfecundation was demonstrated 
      after paternity investigation. RESULT(S): The probability of paternity for twin 1 
      was 99.9999998%, whereas that for twin 2 was excluded on the basis of the 
      following tests: Fy, Pi, human leukocyte antigen (HLA)-DQA1, D1S80, D17S5, HBGG, 
      D5S110, D2S44, and D10S28. CONCLUSION(S): Dizygous twins can have different 
      biologic fathers, as demonstrated in this case. According to published data, the 
      frequency of twins with different fathers is probably underestimated, at least in 
      small selected populations such as those of paternity suits.
FAU - Girela, E
AU  - Girela E
AD  - Department of Legal Medicine, Faculty of Medicine, University of Granada, Spain. 
      EGIRELA@GOLIAT.UGR.ES
FAU - Lorente, J A
AU  - Lorente JA
FAU - Alvarez, J C
AU  - Alvarez JC
FAU - Rodrigo, M D
AU  - Rodrigo MD
FAU - Lorente, M
AU  - Lorente M
FAU - Villanueva, E
AU  - Villanueva E
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Fertil Steril
JT  - Fertility and sterility
JID - 0372772
RN  - 0 (Genetic Markers)
RN  - 0 (HLA-DQ Antigens)
RN  - 0 (HLA-DQ alpha-Chains)
RN  - 0 (HLA-DQA1 antigen)
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Blood Grouping and Crossmatching
MH  - DNA/*analysis
MH  - Female
MH  - *Genetic Markers
MH  - HLA-DQ Antigens/genetics
MH  - HLA-DQ alpha-Chains
MH  - Humans
MH  - Infant, Newborn
MH  - Male
MH  - *Paternity
MH  - Polymerase Chain Reaction
MH  - Polymorphism, Restriction Fragment Length
MH  - Probability
MH  - *Twins, Dizygotic
EDAT- 1997/06/01 00:00
MHDA- 1997/06/01 00:01
CRDT- 1997/06/01 00:00
PHST- 1997/06/01 00:00 [pubmed]
PHST- 1997/06/01 00:01 [medline]
PHST- 1997/06/01 00:00 [entrez]
AID - S0015028297814562 [pii]
AID - 10.1016/s0015-0282(97)81456-2 [doi]
PST - ppublish
SO  - Fertil Steril. 1997 Jun;67(6):1159-61. doi: 10.1016/s0015-0282(97)81456-2.