PMID- 9176795
OWN - NLM
STAT- MEDLINE
DCOM- 19970709
LR  - 20190914
IS  - 0904-2512 (Print)
IS  - 0904-2512 (Linking)
VI  - 26
IP  - 4
DP  - 1997 Apr
TI  - Search for human herpesvirus 6, human cytomegalovirus and varicella zoster virus 
      DNA in recurrent aphthous stomatitis tissue.
PG  - 192-7
AB  - In the present study, the involvement of human herpesvirus 6 (HHV-6), human 
      cytomegalovirus (HCMV) and varicella zoster virus (VZV) in the aetiology of 
      recurrent aphthous stomatitis (RAS) was investigated using the polymerase chain 
      reaction (PCR). Biopsies from 21 RAS patients were analysed, and 20 oral lichen 
      planus (OLP) and 13 normal biopsies were tested as controls. HHV-6-DNA was 
      detected in six of the RAS samples whereas VZV-DNA and HCMV-DNA were not detected 
      in any RAS samples. In the OLP samples, four biopsies were positive for HHV-6-DNA 
      and two were positive for HCMV-DNA. One sample from this group was positive for 
      both HHV-6-DNA and HCMV-DNA. VZV-DNA was not found in any RAS or OLP biopsies. No 
      viral DNA was present in any normal control biopsies. These results do not 
      support an aetiological role for HCMV and VZV in RAS, although the possible 
      involvement of HHV-6 cannot be excluded.
FAU - Ghodratnama, F
AU  - Ghodratnama F
AD  - Infection and Immunity Research Group, University of Glasgow Dental School, UK.
FAU - Riggio, M P
AU  - Riggio MP
FAU - Wray, D
AU  - Wray D
LA  - eng
PT  - Journal Article
PL  - Denmark
TA  - J Oral Pathol Med
JT  - Journal of oral pathology & medicine : official publication of the International 
      Association of Oral Pathologists and the American Academy of Oral Pathology
JID - 8911934
RN  - 0 (DNA, Viral)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Blotting, Southern
MH  - Case-Control Studies
MH  - Cytomegalovirus/isolation & purification
MH  - DNA, Viral/analysis
MH  - Electrophoresis, Agar Gel
MH  - Female
MH  - Herpesvirus 3, Human/isolation & purification
MH  - Herpesvirus 6, Human/isolation & purification
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Polymerase Chain Reaction
MH  - Probability
MH  - Stomatitis, Aphthous/*virology
EDAT- 1997/04/01 00:00
MHDA- 1997/04/01 00:01
CRDT- 1997/04/01 00:00
PHST- 1997/04/01 00:00 [pubmed]
PHST- 1997/04/01 00:01 [medline]
PHST- 1997/04/01 00:00 [entrez]
AID - 10.1111/j.1600-0714.1997.tb00457.x [doi]
PST - ppublish
SO  - J Oral Pathol Med. 1997 Apr;26(4):192-7. doi: 10.1111/j.1600-0714.1997.tb00457.x.