PMID- 9178360
OWN - NLM
STAT- MEDLINE
DCOM- 19970717
LR  - 20191102
IS  - 0926-5287 (Print)
IS  - 0926-5287 (Linking)
VI  - 37
IP  - 2
DP  - 1997
TI  - Inhibition by TGF-beta 1 of the in vitro thymulin-stimulated proliferation of 
      gonocytes from fetal rat testes.
PG  - 203-6
AB  - The cytokine transforming growth factor beta 1 (TGF-beta 1) inhibits the growth 
      of certain cells and the differentiation of others. A thymus hormone, thymulin, 
      stimulated the proliferation of fetal male germ cells in explants of testes from 
      13.5 gestation day rat fetuses. The way in which thymulin acts is unknown. Adding 
      TGF-beta 1 to the culture medium blocked the response of the fetal male rat germ 
      cells to thymulin. We suggest that TGF-beta 1 and thymulin may thus influence the 
      same metabolic chain of events.
FAU - Prepin, J
AU  - Prepin J
AD  - Departement de cytologie et histologie, universite Paris V-Rene-Descartes, 
      France.
FAU - Le Vigouroux, P
AU  - Le Vigouroux P
LA  - eng
PT  - Journal Article
PL  - France
TA  - Reprod Nutr Dev
JT  - Reproduction, nutrition, development
JID - 8913069
RN  - 0 (Transforming Growth Factor beta)
RN  - 9H198D04WL (Thymic Factor, Circulating)
SB  - IM
MH  - Animals
MH  - Cell Division/*drug effects
MH  - Gestational Age
MH  - Male
MH  - Organ Culture Techniques
MH  - Rats
MH  - Rats, Wistar
MH  - Spermatozoa/*cytology
MH  - Testis/*cytology/*embryology
MH  - Thymic Factor, Circulating/*pharmacology
MH  - Transforming Growth Factor beta/*pharmacology
EDAT- 1997/01/01 00:00
MHDA- 1997/01/01 00:01
CRDT- 1997/01/01 00:00
PHST- 1997/01/01 00:00 [pubmed]
PHST- 1997/01/01 00:01 [medline]
PHST- 1997/01/01 00:00 [entrez]
AID - S092652879781581X [pii]
AID - 10.1051/rnd:19970207 [doi]
PST - ppublish
SO  - Reprod Nutr Dev. 1997;37(2):203-6. doi: 10.1051/rnd:19970207.