PMID- 9179500 OWN - NLM STAT- MEDLINE DCOM- 19970806 LR - 20190512 IS - 1340-2838 (Print) IS - 1340-2838 (Linking) VI - 4 IP - 1 DP - 1997 Feb 28 TI - Assignment of human membrane-type matrix metalloproteinase-2 (MT2-MMP) gene to 16q12 by FISH and PCR-based human/rodent cell hybrid mapping panel analysis. PG - 77-9 AB - A new group of matrix metalloproteinase with a potential membrane domain was reported as membrane-type matrix metalloproteinases (MT-MMPs), and the gene coding for one of them, MT2-MMP was recently cloned from a human lung cDNA library. To predict its physiological functions by the relation to the genetic disorders mapped on the chromosomes, the chromosomal location of the human MT2-MMP gene was examined by fluorescence in situ hybridization (FISH) and PCR-based analysis with human/rodent hybrid cell mapping panels, and it was assigned to 16q12. FAU - Yasumitsu, H AU - Yasumitsu H AD - Division of Cell Biology, Kihara Institute for Biological Research, Yokohama City University, Japan. FAU - Shofuda, K AU - Shofuda K FAU - Nishihashi, A AU - Nishihashi A FAU - Eki, T AU - Eki T FAU - Koshikawa, N AU - Koshikawa N FAU - Mizushima, H AU - Mizushima H FAU - Miyazaki, K AU - Miyazaki K LA - eng PT - Journal Article PL - England TA - DNA Res JT - DNA research : an international journal for rapid publication of reports on genes and genomes JID - 9423827 RN - 0 (MMP15 protein, human) RN - EC 3.4.24.- (Matrix Metalloproteinase 15) RN - EC 3.4.24.- (Matrix Metalloproteinases, Membrane-Associated) RN - EC 3.4.24.- (Metalloendopeptidases) SB - IM MH - Animals MH - Chromosome Mapping/*methods MH - *Chromosomes, Human, Pair 16 MH - Humans MH - Hybrid Cells MH - In Situ Hybridization, Fluorescence MH - Matrix Metalloproteinase 15 MH - Matrix Metalloproteinases, Membrane-Associated MH - Metalloendopeptidases/*genetics MH - Polymerase Chain Reaction/methods MH - Rodentia EDAT- 1997/02/28 00:00 MHDA- 1997/02/28 00:01 CRDT- 1997/02/28 00:00 PHST- 1997/02/28 00:00 [pubmed] PHST- 1997/02/28 00:01 [medline] PHST- 1997/02/28 00:00 [entrez] AID - 10.1093/dnares/4.1.77 [doi] PST - ppublish SO - DNA Res. 1997 Feb 28;4(1):77-9. doi: 10.1093/dnares/4.1.77.