PMID- 9189042 OWN - NLM STAT- MEDLINE DCOM- 19970710 LR - 20061115 IS - 0364-5134 (Print) IS - 0364-5134 (Linking) VI - 41 IP - 6 DP - 1997 Jun TI - Human T-cell lymphotropic virus type I-associated facial nerve palsy in Trinidad and Tobago. PG - 806-9 AB - To assess the association of the human T-cell lymphotropic virus type I (HTLV-I) and idiopathic facial nerve palsy of the lower motor neuron type, we studied 78 patients consecutively admitted to the Port of Spain General Hospital in Trinidad, the West Indies, with a confirmed diagnosis of idiopathic facial nerve palsy. Patients were compared with two control groups: a population-based group of persons 20 years and older and a hospital-based group of patients 15 to 84 years old admitted to the medical wards. Sixty-two patients were Trinidadians of African origin and 16 were Trinidadians of East Indian origin. None of the East Indian patients was HTLV-I antibody positive. Three Afro-Trinidadians were infected with human immunodeficiency virus type 1 and 1 was coinfected with this virus and HTLV-I. Of the remaining 58 Afro-Trinidadians, 12 (20.7%) were HTLV-I positive only. This rate was statistically higher than the HTLV-I seroprevalence in the Afro-Trinidadian general population (3.5%) and the hospital control group (5.6%). After age standardization, the HTLV-I prevalence for patients with facial nerve palsy remained significantly elevated. HTLV-I antibody assays should be performed on all patients with idiopathic facial nerve palsy of the lower motor neuron type who live in HTLV-I endemic areas or are migrants from these areas. FAU - Bartholomew, C AU - Bartholomew C AD - University of the West Indies Department of Medicine, Port of Spain, Trinidad, West Indies. FAU - Cleghorn, F AU - Cleghorn F FAU - Jack, N AU - Jack N FAU - Edwards, J AU - Edwards J FAU - Blattner, W AU - Blattner W LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PL - United States TA - Ann Neurol JT - Annals of neurology JID - 7707449 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Blotting, Western MH - Deltaretrovirus Infections/*complications/diagnosis/epidemiology MH - Facial Paralysis/*virology MH - Female MH - *Human T-lymphotropic virus 1 MH - Humans MH - Male MH - Middle Aged MH - Prevalence MH - Serologic Tests MH - Trinidad and Tobago RF - 16 EDAT- 1997/06/01 00:00 MHDA- 1997/06/01 00:01 CRDT- 1997/06/01 00:00 PHST- 1997/06/01 00:00 [pubmed] PHST- 1997/06/01 00:01 [medline] PHST- 1997/06/01 00:00 [entrez] AID - 10.1002/ana.410410617 [doi] PST - ppublish SO - Ann Neurol. 1997 Jun;41(6):806-9. doi: 10.1002/ana.410410617.