PMID- 9189914
OWN - NLM
STAT- MEDLINE
DCOM- 19970731
LR  - 20190718
IS  - 0959-4965 (Print)
IS  - 0959-4965 (Linking)
VI  - 8
IP  - 7
DP  - 1997 May 6
TI  - Urine and urine-derived compounds induce c-fos mRNA expression in accessory 
      olfactory bulb.
PG  - 1679-83
AB  - Soiled bedding from male mice induced c-fos mRNA expression in the accessory 
      olfactory bulb (AOB) and main olfactory bulb (MOB) of female mice. The increase 
      observed in the AOB, but not the MOB, was dependent on the presence of the 
      vomeronasal organ (VNO). Male urine alone also increased c-fos mRNA expression in 
      the AOB. The urine-derived compounds dehydro-exo-brevicomin (DHB) and 
      sec-butyl-dihydrothiazole (SBT) in combination with major urinary protein (MUP) 
      induced significantly greater c-fos mRNA expression in the AOB than in the MOB. 
      The results indicate that compounds derived from male urine are detected at the 
      AOB and suggest that specific urinary compounds play an important role in 
      AOB-mediated reproductive events.
FAU - Guo, J
AU  - Guo J
AD  - Department of Texas Southwestern Medical Center, Dallas 75235, USA.
FAU - Zhou, A
AU  - Zhou A
FAU - Moss, R L
AU  - Moss RL
LA  - eng
GR  - DC02120/DC/NIDCD NIH HHS/United States
GR  - MH41784/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - England
TA  - Neuroreport
JT  - Neuroreport
JID - 9100935
RN  - 0 (Alpha-Globulins)
RN  - 0 (Bridged Bicyclo Compounds, Heterocyclic)
RN  - 0 (Pheromones)
RN  - 0 (Proteins)
RN  - 0 (Proto-Oncogene Proteins c-fos)
RN  - 0 (RNA, Messenger)
RN  - 0 (major urinary proteins)
RN  - KPU1SW45CD (brevicomin)
SB  - IM
MH  - Alpha-Globulins/analysis/physiology
MH  - Amygdala/drug effects/metabolism
MH  - Animals
MH  - Autoradiography
MH  - Blotting, Northern
MH  - Bridged Bicyclo Compounds, Heterocyclic/analysis/pharmacology
MH  - Female
MH  - Male
MH  - Mice
MH  - Mice, Inbred C57BL
MH  - Mice, Inbred ICR
MH  - Olfactory Bulb/*drug effects/metabolism
MH  - Pheromones/analysis/*physiology
MH  - Proteins
MH  - Proto-Oncogene Proteins c-fos/drug effects/*metabolism
MH  - RNA, Messenger/metabolism
MH  - Urine/*chemistry/*physiology
EDAT- 1997/05/06 00:00
MHDA- 1997/05/06 00:01
CRDT- 1997/05/06 00:00
PHST- 1997/05/06 00:00 [pubmed]
PHST- 1997/05/06 00:01 [medline]
PHST- 1997/05/06 00:00 [entrez]
AID - 10.1097/00001756-199705060-00024 [doi]
PST - ppublish
SO  - Neuroreport. 1997 May 6;8(7):1679-83. doi: 10.1097/00001756-199705060-00024.