PMID- 9192707
OWN - NLM
STAT- MEDLINE
DCOM- 19980910
LR  - 20190914
IS  - 0022-149X (Print)
IS  - 0022-149X (Linking)
VI  - 71
IP  - 2
DP  - 1997 Jun
TI  - Comparison of human and murine isolates of Schistosoma mansoni from Richard-Toll, 
      Senegal, by isoelectric focusing.
PG  - 175-81
AB  - Studies on human and murine isolates of Schistosoma mansoni, from Richard-Toll, 
      Senegal, were carried out by isoelectric focusing in polyacrylamide gels. Seven 
      enzyme systems; lactate dehydrogenase (LDH), malate dehydrogenase (MDH), 
      glucose-6-phosphate dehydrogenase (G6PD), acid phosphatase (AcP), hexokinase 
      (HK), glucose phosphate isomerase (GPI), and phosphoglucomutase (PGM), were used 
      to compare the two isolates. All systems tested, apart from LDH, were found to be 
      polymorphic for both isolates. Interestingly, one phenotype is more frequent than 
      the remainder. The results show that there is no significant genetic variation 
      between the S. mansoni isolates from man and the rodents, Arvicanthis niloticus 
      and Mastomys huberti.
FAU - Sene, M
AU  - Sene M
AD  - Programme 'Eau et Sante', ORSTOM, Dakar, Senegal.
FAU - Bremond, P
AU  - Bremond P
FAU - Herve, J P
AU  - Herve JP
FAU - Southgate, V R
AU  - Southgate VR
FAU - Sellin, B
AU  - Sellin B
FAU - Marchand, B
AU  - Marchand B
FAU - Duplantier, J M
AU  - Duplantier JM
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Helminthol
JT  - Journal of helminthology
JID - 2985115R
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
RN  - EC 1.1.1.37 (Malate Dehydrogenase)
RN  - EC 1.1.1.49 (Glucosephosphate Dehydrogenase)
RN  - EC 2.7.1.1 (Hexokinase)
RN  - EC 3.1.3.2 (Acid Phosphatase)
RN  - EC 5.3.1.9 (Glucose-6-Phosphate Isomerase)
RN  - EC 5.4.2.2 (Phosphoglucomutase)
SB  - IM
MH  - Acid Phosphatase/chemistry
MH  - Animal Diseases/parasitology
MH  - Animals
MH  - Genetic Variation
MH  - Glucose-6-Phosphate Isomerase/chemistry
MH  - Glucosephosphate Dehydrogenase/chemistry
MH  - Hexokinase/chemistry
MH  - Humans
MH  - Isoelectric Focusing
MH  - L-Lactate Dehydrogenase/chemistry
MH  - Malate Dehydrogenase/chemistry
MH  - Phenotype
MH  - Phosphoglucomutase/chemistry
MH  - Rats
MH  - Schistosoma mansoni/enzymology/*genetics
MH  - Schistosomiasis mansoni/parasitology
MH  - Senegal
EDAT- 1997/06/01 00:00
MHDA- 1997/06/01 00:01
CRDT- 1997/06/01 00:00
PHST- 1997/06/01 00:00 [pubmed]
PHST- 1997/06/01 00:01 [medline]
PHST- 1997/06/01 00:00 [entrez]
AID - 10.1017/s0022149x00015868 [doi]
PST - ppublish
SO  - J Helminthol. 1997 Jun;71(2):175-81. doi: 10.1017/s0022149x00015868.