PMID- 9202370 OWN - NLM STAT- MEDLINE DCOM- 19970717 LR - 20190622 IS - 0002-9149 (Print) IS - 0002-9149 (Linking) VI - 79 IP - 12 DP - 1997 Jun 15 TI - Serum levels of soluble form of Fas molecule in patients with congestive heart failure. PG - 1698-701 AB - Compared with soluble Fas molecule (sFas, an inhibitor of Fas-mediated apoptosis) in normal volunteers, the serum level of sFas significantly increased by 41% in New York Heart Association (NYHA) class III (p <0.05) and by 97% in NYHA class IV patients with congestive heart failure (p <0.001). Furthermore, sFas showed correlations with soluble forms of TNF receptor-p55 (RI) and -p75 (RII) (r = 0.68 and r = 0.56) which inhibit activities of TNF alpha. FAU - Okuyama, M AU - Okuyama M AD - The First Department of Internal Medicine, Yamagata University Medical School, Japan. FAU - Yamaguchi, S AU - Yamaguchi S FAU - Nozaki, N AU - Nozaki N FAU - Yamaoka, M AU - Yamaoka M FAU - Shirakabe, M AU - Shirakabe M FAU - Tomoike, H AU - Tomoike H LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Am J Cardiol JT - The American journal of cardiology JID - 0207277 RN - 0 (Receptors, Tumor Necrosis Factor) RN - 0 (fas Receptor) SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Heart Failure/*blood/classification/etiology MH - Humans MH - Male MH - Middle Aged MH - Molecular Weight MH - Receptors, Tumor Necrosis Factor/blood MH - fas Receptor/*blood EDAT- 1997/06/15 00:00 MHDA- 1997/06/15 00:01 CRDT- 1997/06/15 00:00 PHST- 1997/06/15 00:00 [pubmed] PHST- 1997/06/15 00:01 [medline] PHST- 1997/06/15 00:00 [entrez] AID - S0002914997002282 [pii] AID - 10.1016/s0002-9149(97)00228-2 [doi] PST - ppublish SO - Am J Cardiol. 1997 Jun 15;79(12):1698-701. doi: 10.1016/s0002-9149(97)00228-2.