PMID- 9212120 OWN - NLM STAT- MEDLINE DCOM- 19970723 LR - 20190704 IS - 0003-2999 (Print) IS - 0003-2999 (Linking) VI - 85 IP - 1 DP - 1997 Jul TI - The incidence of latex sensitivity in ambulatory surgical patients: a correlation of historical factors with positive serum immunoglobin E levels. PG - 44-9 AB - Increasing reports of latex-induced anaphylaxis make preoperative identification of latex-sensitive individuals an important concern. The incidence of latex sensitivity and the efficacy of questionnaires in identifying this in ambulatory surgical populations have not been determined. To clarify these issues, 996 ambulatory surgical patients were studied preoperatively. A questionnaire addressing demographic information, previous surgeries, history of atopy, previous exposure or reactions to latex, congenital abnormalities, and food allergies was administered. These data were then compared with serum anti-latex immunoglobin E (IgE) levels (AlaSTAT test), and risk factors, sensitivity, and specificity were determined. Of this population, 6.7% had IgE antibodies against latex (i.e., latex sensitivity). Male gender, non-Caucasian race, age, asthma, spinal cord abnormalities, food allergies, stated latex allergy, and symptoms when exposed to latex increased the risk of latex sensitivity. The specificity and positive predictive value of history were low. No systemic allergic reactions occurred, a finding that could be attributed to chance alone. The incidence of latex sensitivity in this population suggests that latex allergy is a significant potential problem in ambulatory surgical patients. History, however, does not appear to be a reliable predictor of the presence of anti-latex antibodies. FAU - Lebenbom-Mansour, M H AU - Lebenbom-Mansour MH AD - Department of Anesthesiology, Sinai Health System, Detroit, Michigan, USA. FAU - Oesterle, J R AU - Oesterle JR FAU - Ownby, D R AU - Ownby DR FAU - Jennett, M K AU - Jennett MK FAU - Post, S K AU - Post SK FAU - Zaglaniczy, K AU - Zaglaniczy K LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Anesth Analg JT - Anesthesia and analgesia JID - 1310650 RN - 0 (Latex) RN - 37341-29-0 (Immunoglobulin E) SB - IM CIN - Anesth Analg. 1998 Apr;86(4):919. PMID: 9539634 MH - *Ambulatory Surgical Procedures MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Humans MH - Hypersensitivity, Immediate/*diagnosis/etiology MH - Immunoglobulin E/*blood MH - Latex/*adverse effects MH - Male MH - Medical History Taking MH - Odds Ratio MH - Predictive Value of Tests MH - Risk Factors MH - Sensitivity and Specificity MH - Surveys and Questionnaires EDAT- 1997/07/01 00:00 MHDA- 1997/07/01 00:01 CRDT- 1997/07/01 00:00 PHST- 1997/07/01 00:00 [pubmed] PHST- 1997/07/01 00:01 [medline] PHST- 1997/07/01 00:00 [entrez] AID - 10.1097/00000539-199707000-00008 [doi] PST - ppublish SO - Anesth Analg. 1997 Jul;85(1):44-9. doi: 10.1097/00000539-199707000-00008.