PMID- 9219063
OWN - NLM
STAT- MEDLINE
DCOM- 19970909
LR  - 20191114
IS  - 0887-8013 (Print)
IS  - 1098-2825 (Electronic)
IS  - 0887-8013 (Linking)
VI  - 11
IP  - 4
DP  - 1997
TI  - Evaluation of the second generation IMx Toxo IgG antibody assay for detection of 
      antibodies to Toxoplasma gondii in human sera.
PG  - 214-9
AB  - For an evaluation of the Abbott IMx Toxo IgG second generation, antibodies to 
      Toxoplasma gondii were detected by Abbott IMx Toxo IgG and IgM, Vidas Toxo IgG 
      and Toxo IgM (bioMerieux, France) with immunofluorescence assay verified by the 
      dye-test for IgG, and immunosorbent agglutination assay (ISAGA) for IgM as 
      references. The study included 507 serum samples collected over one month in two 
      laboratories, 32 samples from HIV-infected patients, and 70 serial samples from 
      23 women surveyed for seroconversion or persistent IgM. After exclusion of nine 
      equivocal results from the 507 samples, the sensitivity and specificity, 
      respectively, were 100% (156/156) and 100% (342/342) for the IMx Toxo IgG and 
      98.1% (153/156) and 100% (342/342) for the Vidas Toxo IgG. Of the 32 HIV-infected 
      patient samples, 7 gave false positive results with IMx Toxo IgG. This was 
      because the samples had been heated. In 5 of the 70 serial samples. IMx Toxo IgG 
      gave positive results earlier than Vidas Toxo IgG and in two cases earlier than 
      IgM antibody assays. In this study IMx Toxo IgG second generation showed an 
      increase in sensitivity and specificity in comparison with data reported 
      previously for the first generation.
FAU - De Champs, C
AU  - De Champs C
AD  - Departement de Parasitologie, Mycologie Medicale et Moleculaire, Centre 
      Hospitalier Universitaire, Grenoble, France.
FAU - Pelloux, H
AU  - Pelloux H
FAU - Cambon, M
AU  - Cambon M
FAU - Fricker-Hidalgo, H
AU  - Fricker-Hidalgo H
FAU - Goullier-Fleuret, A
AU  - Goullier-Fleuret A
FAU - Ambroise-Thomas, P
AU  - Ambroise-Thomas P
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - J Clin Lab Anal
JT  - Journal of clinical laboratory analysis
JID - 8801384
RN  - 0 (Antibodies, Protozoan)
RN  - 0 (Immunoglobulin G)
RN  - 0 (Immunoglobulin M)
SB  - IM
MH  - AIDS-Related Opportunistic Infections/diagnosis/immunology
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Animals
MH  - Antibodies, Protozoan/*blood
MH  - Child
MH  - Child, Preschool
MH  - Evaluation Studies as Topic
MH  - False Positive Reactions
MH  - Female
MH  - Humans
MH  - *Immunoenzyme Techniques/statistics & numerical data
MH  - Immunoglobulin G/*blood
MH  - Immunoglobulin M/blood
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Middle Aged
MH  - Pregnancy
MH  - Pregnancy Complications, Parasitic/diagnosis/immunology
MH  - Sensitivity and Specificity
MH  - Toxoplasma/*immunology
MH  - Toxoplasmosis/complications/diagnosis/immunology
PMC - PMC6760745
EDAT- 1997/01/01 00:00
MHDA- 2000/06/20 09:00
PMCR- 1998/12/07
CRDT- 1997/01/01 00:00
PHST- 1997/01/01 00:00 [pubmed]
PHST- 2000/06/20 09:00 [medline]
PHST- 1997/01/01 00:00 [entrez]
PHST- 1998/12/07 00:00 [pmc-release]
AID - 10.1002/(SICI)1098-2825(1997)11:4<214::AID-JCLA7>3.0.CO;2-8 [pii]
AID - JCLA7 [pii]
AID - 10.1002/(sici)1098-2825(1997)11:4<214::aid-jcla7>3.0.co;2-8 [doi]
PST - ppublish
SO  - J Clin Lab Anal. 1997;11(4):214-9. doi: 
      10.1002/(sici)1098-2825(1997)11:4<214::aid-jcla7>3.0.co;2-8.