PMID- 9220613 OWN - NLM STAT- MEDLINE DCOM- 19970912 LR - 20190831 IS - 0378-1135 (Print) IS - 0378-1135 (Linking) VI - 55 IP - 1-4 DP - 1997 Apr TI - General overview of PRRSV: a perspective from the United States. PG - 187-96 AB - Four years after the report of its discovery, porcine reproductive and respiratory syndrome virus (PRRSV) continues to challenge swine producers, veterinary practitioners, and animal health researchers in the United States. The prevalence of infection is high--60% to 80% of herds is a reasonable estimate--but the clinical effects of infection vary widely among farms. In many herds, infection is unapparent and productivity seemingly unaffected. Some infected herds report occasional respiratory disease outbreaks in young pigs, or periodic outbreaks of reproductive disease, and a few herds experience severe, chronic disease problems, particularly in young pigs. In these herds, secondary infections with viral or bacterial pathogens, particularly Salmonella choleraesuis, Streptococcus suis, or Haemophilus parasuis typically occur concurrently with PRRSV infections. Understanding why some herds undergo devastating episodes of clinical disease and others show no apparent effects is central to solving the problem of clinical PRRS for swine producers. Understanding the ecology and epidemiology of PRRSV is the key to preventing and controlling PRRSV in the future. The objective of this article is to review recent developments in these areas. FAU - Zimmerman, J J AU - Zimmerman JJ AD - Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Iowa State University, Ames 50011, USA. jjzimm@cvm01.vm.iastate.edu FAU - Yoon, K J AU - Yoon KJ FAU - Wills, R W AU - Wills RW FAU - Swenson, S L AU - Swenson SL LA - eng PT - Journal Article PT - Review PL - Netherlands TA - Vet Microbiol JT - Veterinary microbiology JID - 7705469 SB - IM MH - Abortion, Veterinary/virology MH - Animals MH - Cross-Sectional Studies MH - Disease Outbreaks/veterinary MH - Female MH - Haemophilus Infections/complications/epidemiology/veterinary MH - Porcine Reproductive and Respiratory Syndrome/diagnosis/*epidemiology/immunology MH - *Porcine respiratory and reproductive syndrome virus MH - Pregnancy MH - Salmonella Infections, Animal/complications/epidemiology MH - Streptococcal Infections/complications/epidemiology/veterinary MH - Streptococcus suis MH - Swine MH - Swine Diseases MH - United States/epidemiology RF - 43 EDAT- 1997/04/01 00:00 MHDA- 1997/04/01 00:01 CRDT- 1997/04/01 00:00 PHST- 1997/04/01 00:00 [pubmed] PHST- 1997/04/01 00:01 [medline] PHST- 1997/04/01 00:00 [entrez] AID - S0378-1135(96)01330-2 [pii] AID - 10.1016/s0378-1135(96)01330-2 [doi] PST - ppublish SO - Vet Microbiol. 1997 Apr;55(1-4):187-96. doi: 10.1016/s0378-1135(96)01330-2.