PMID- 9220626
OWN - NLM
STAT- MEDLINE
DCOM- 19970912
LR  - 20190831
IS  - 0378-1135 (Print)
IS  - 0378-1135 (Linking)
VI  - 55
IP  - 1-4
DP  - 1997 Apr
TI  - Indirect fluorescent IgM antibody response of pigs infected with porcine 
      reproductive and respiratory syndrome syndrome virus.
PG  - 303-7
AB  - IgG and IgM antibody responses were examined by an indirect fluorescent antibody 
      method in pigs following inoculation with different porcine reproductive and 
      respiratory syndrome virus (PRRSV) isolates or a vaccine virus. Viremia was also 
      examined in the pigs. The IgG antibody was first detected between 9 and 14 days 
      post inoculation (PI) and maintained high titers for at least 7 weeks PI. No 
      change in IgG antibody titers was observed when the pigs were reinoculated with 
      PRRSV 35 days PI. IgM antibody was detected between 5 and 28 days PI in the pigs. 
      Reinoculation at 35 days PI caused a short term rise of IgM antibody. Virus was 
      isolated from sera collected between 2 and 21 days PI. The IgM antibody was 
      detected regularly in sera collected during viremia and up to 1-2 weeks after the 
      viremic periods. These results suggest that pigs with detectable IgM antibody are 
      probably pigs with recent infection and that routine testing of IgM antibody in 
      purchased breeding pigs from seropositive farms may be useful in identification 
      of pigs with recent infection.
FAU - Joo, H S
AU  - Joo HS
AD  - College of Veterinary Medicine, University of Minnesota, St. Paul 55108, USA.
FAU - Park, B K
AU  - Park BK
FAU - Dee, S A
AU  - Dee SA
FAU - Pijoan, C
AU  - Pijoan C
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Vet Microbiol
JT  - Veterinary microbiology
JID - 7705469
RN  - 0 (Antibodies, Viral)
RN  - 0 (Immunoglobulin G)
RN  - 0 (Immunoglobulin M)
SB  - IM
MH  - Animals
MH  - Antibodies, Viral/*blood
MH  - Fluorescent Antibody Technique, Indirect
MH  - Immunoglobulin G/blood
MH  - Immunoglobulin M/*blood
MH  - Porcine Reproductive and Respiratory Syndrome/blood/diagnosis/*immunology
MH  - Porcine respiratory and reproductive syndrome virus/*immunology
MH  - Swine
MH  - Time Factors
MH  - Viremia/blood/diagnosis/immunology
EDAT- 1997/04/01 00:00
MHDA- 1997/04/01 00:01
CRDT- 1997/04/01 00:00
PHST- 1997/04/01 00:00 [pubmed]
PHST- 1997/04/01 00:01 [medline]
PHST- 1997/04/01 00:00 [entrez]
AID - S0378-1135(96)01332-6 [pii]
AID - 10.1016/s0378-1135(96)01332-6 [doi]
PST - ppublish
SO  - Vet Microbiol. 1997 Apr;55(1-4):303-7. doi: 10.1016/s0378-1135(96)01332-6.