PMID- 9221462 OWN - NLM STAT- MEDLINE DCOM- 19970714 LR - 20201209 IS - 0035-3639 (Print) IS - 0035-3639 (Linking) VI - 18 IP - 2 DP - 1997 Apr TI - [Digestive and extra-digestive complications of nonsteroidal anti-inflammatory drugs. Preventive and curative strategies]. PG - 52-8 AB - The authors review the digestive ulceration risk factors and the criteria for selecting a non steroidal antiinflammatory (NSAI), included the most recent drugs, such as selective anti-cyclo-oxygenases 2. They actualize the preventive strategies and insist on the values of misoprostol and of slow acting anti-rheumatic drugs. In the case of digestive ulcerations, they plead for the immediate stop of the NSAI and its replacement if necessary by corticosteroids, for the prescription of a proton pump inhibitor (PPI) or mesalazine according to the localisation of the lesion, finally for the eradication within 8 days of Helicobacter pylori. FAU - Sternon, J AU - Sternon J AD - Service de Medecine Interne, Hopital Erasme, Bruxelles. FAU - Adler, M AU - Adler M LA - fre PT - Journal Article PT - Review TT - Les complications digestives et extra-digestives des anti-inflammatoires non steroidiens. Strategies preventives et curatives. PL - Belgium TA - Rev Med Brux JT - Revue medicale de Bruxelles JID - 8003474 RN - 0 (Anti-Inflammatory Agents) RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) RN - 0 (Anti-Ulcer Agents) RN - 0 (Cyclooxygenase Inhibitors) RN - 0 (Steroids) RN - 0E43V0BB57 (Misoprostol) RN - 3XC8GUZ6CB (Sulfasalazine) SB - IM MH - Anti-Inflammatory Agents/therapeutic use MH - Anti-Inflammatory Agents, Non-Steroidal/*adverse effects MH - Anti-Ulcer Agents/therapeutic use MH - Cyclooxygenase Inhibitors/therapeutic use MH - Drug Interactions MH - Helicobacter Infections/complications/drug therapy/microbiology MH - Helicobacter pylori MH - Humans MH - Misoprostol/therapeutic use MH - Peptic Ulcer/*chemically induced/microbiology/prevention & control MH - Steroids MH - Sulfasalazine/therapeutic use RF - 43 EDAT- 1997/04/01 00:00 MHDA- 1997/04/01 00:01 CRDT- 1997/04/01 00:00 PHST- 1997/04/01 00:00 [pubmed] PHST- 1997/04/01 00:01 [medline] PHST- 1997/04/01 00:00 [entrez] PST - ppublish SO - Rev Med Brux. 1997 Apr;18(2):52-8.