PMID- 9238316
OWN - NLM
STAT- MEDLINE
DCOM- 19970814
LR  - 20191102
IS  - 0733-8635 (Print)
IS  - 0733-8635 (Linking)
VI  - 14
IP  - 4
DP  - 1996 Oct
TI  - Growth factors in hair organ development and the hair growth cycle.
PG  - 559-72
AB  - Growth factors are polypeptides that regulate growth and differentiation of many 
      cell types. Different growth factor families including the epidermal growth 
      factor (EGF)-related ligands, fibroblast growth factors (FGF), transforming 
      growth factor-beta (TGF-beta), insulin-like growth factor (IGF), hepatocyte 
      growth factor/scatter factor (HGF/SF), and platelet-derived growth factor (PDGF) 
      have been shown to be crucial for the regulation of the hair cycle and hair 
      growth. Growth factors and their receptors have been localized to the skin and 
      hair follicles. Their biological activities on cells comprising the hair follicle 
      have been tested in vitro and increasingly in transgenic mice. Herein we review 
      selected important aspects of growth factors with regard to the hair organ, its 
      development, and the hair growth cycle.
FAU - Peus, D
AU  - Peus D
AD  - Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA.
FAU - Pittelkow, M R
AU  - Pittelkow MR
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - United States
TA  - Dermatol Clin
JT  - Dermatologic clinics
JID - 8300886
RN  - 0 (Growth Substances)
SB  - IM
MH  - Animals
MH  - Growth Substances/*physiology
MH  - Hair/*growth & development
MH  - Humans
MH  - Mice
MH  - Mice, Transgenic
MH  - Morphogenesis
MH  - Reference Values
MH  - Signal Transduction/physiology
RF  - 129
EDAT- 1996/10/01 00:00
MHDA- 1996/10/01 00:01
CRDT- 1996/10/01 00:00
PHST- 1996/10/01 00:00 [pubmed]
PHST- 1996/10/01 00:01 [medline]
PHST- 1996/10/01 00:00 [entrez]
AID - S0733-8635(05)70384-3 [pii]
AID - 10.1016/s0733-8635(05)70384-3 [doi]
PST - ppublish
SO  - Dermatol Clin. 1996 Oct;14(4):559-72. doi: 10.1016/s0733-8635(05)70384-3.