PMID- 9251151
OWN - NLM
STAT- MEDLINE
DCOM- 19970930
LR  - 20220408
IS  - 0033-3174 (Print)
IS  - 0033-3174 (Linking)
VI  - 59
IP  - 4
DP  - 1997 Jul-Aug
TI  - Marital conflict in older adults: endocrinological and immunological correlates.
PG  - 339-49
AB  - OBJECTIVE: To assess endocrinological and immunological correlates of marital 
      conflict and marital satisfaction, 31 older couples (mean age 67 years) who had 
      been married an average of 42 years were studied. METHOD: Couples were admitted 
      to the Clinical Research Center and a catheter was placed in each subject's arm. 
      Blood was drawn on entry for immunological assays; for hormone analyses, five 
      blood samples were drawn during a 30-minute conflict discussion and a 15-minute 
      recovery session. The conflict session was recorded on videotapes that were later 
      coded for problem-solving behaviors using the Marital Interaction Coding System 
      (MICS). RESULTS: Among wives, escalation of negative behavior during conflict and 
      marital satisfaction showed strong relationships to endocrine changes, accounting 
      for 16% to 21% of the variance in the rates of change of cortisol, 
      adrenocorticotropic hormone (ACTH), and norepinephrine (but not epinephrine). In 
      contrast, husbands' endocrine data did not show significant relationships with 
      negative behavior or marital quality. Both men and women who showed relatively 
      poorer immunological responses across three functional assays (the blastogenic 
      response to two T-cell mitogens and antibody titers to latent Epstein-Barr virus) 
      displayed more negative behavior during conflict; they also characterized their 
      usual marital disagreements as more negative than individuals who showed better 
      immune responses across assays. CONCLUSION: Abrasive marital interactions may 
      have physiological consequences even among older adults in long-term marriages.
FAU - Kiecolt-Glaser, J K
AU  - Kiecolt-Glaser JK
AD  - Department of Psychiatry, Ohio State University, Columbus, USA.
FAU - Glaser, R
AU  - Glaser R
FAU - Cacioppo, J T
AU  - Cacioppo JT
FAU - MacCallum, R C
AU  - MacCallum RC
FAU - Snydersmith, M
AU  - Snydersmith M
FAU - Kim, C
AU  - Kim C
FAU - Malarkey, W B
AU  - Malarkey WB
LA  - eng
GR  - CA16058/CA/NCI NIH HHS/United States
GR  - MH44660/MH/NIMH NIH HHS/United States
GR  - MO1-RR-0034/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Psychosom Med
JT  - Psychosomatic medicine
JID - 0376505
RN  - 0 (Antibodies, Viral)
RN  - 0 (Antigens, Viral)
RN  - 0 (Capsid Proteins)
RN  - 0 (Epstein-Barr viral capsid antigen)
RN  - 0 (Hormones)
RN  - 0 (Immunoglobulin G)
RN  - 9002-60-2 (Adrenocorticotropic Hormone)
RN  - WI4X0X7BPJ (Hydrocortisone)
RN  - X4W3ENH1CV (Norepinephrine)
RN  - YKH834O4BH (Epinephrine)
SB  - IM
CIN - Psychosom Med. 1997 Jul-Aug;59(4):350-1. PMID: 9251152
MH  - Adrenocorticotropic Hormone/blood
MH  - Adult
MH  - Aged
MH  - Aging/physiology/*psychology
MH  - Antibodies, Viral/blood
MH  - Antibody Formation/*immunology
MH  - Antigens, Viral/immunology
MH  - Arousal/*physiology
MH  - *Capsid Proteins
MH  - *Conflict, Psychological
MH  - Epinephrine/blood
MH  - Female
MH  - Hormones/*blood
MH  - Humans
MH  - Hydrocortisone/blood
MH  - Immunoglobulin G/blood
MH  - Lymphocyte Activation/*immunology
MH  - Male
MH  - Marriage/*psychology
MH  - Middle Aged
MH  - Norepinephrine/blood
MH  - Personality Assessment
MH  - Psychoneuroimmunology
EDAT- 1997/07/01 00:00
MHDA- 1997/07/01 00:01
CRDT- 1997/07/01 00:00
PHST- 1997/07/01 00:00 [pubmed]
PHST- 1997/07/01 00:01 [medline]
PHST- 1997/07/01 00:00 [entrez]
AID - 10.1097/00006842-199707000-00001 [doi]
PST - ppublish
SO  - Psychosom Med. 1997 Jul-Aug;59(4):339-49. doi: 10.1097/00006842-199707000-00001.