PMID- 9263603
OWN - NLM
STAT- MEDLINE
DCOM- 19971001
LR  - 20190831
IS  - 0165-3806 (Print)
IS  - 0165-3806 (Linking)
VI  - 101
IP  - 1-2
DP  - 1997 Jul 18
TI  - Carbon monoxide formation in the guinea pig hippocampus: ontogeny and effect of 
      in vitro ethanol exposure.
PG  - 283-6
AB  - Carbon monoxide (CO) is considered to be a novel neuronal messenger in the brain, 
      similar to nitric oxide. The ontogeny of CO formation in transverse hippocampal 
      slices of the guinea pig was elucidated at selected prenatal and postnatal ages, 
      and the effect of in vitro ethanol exposure on hippocampal CO formation was 
      determined. There was a higher rate of hippocampal CO formation in the fetus at 
      gestational day (GD) 50 and GD 62 (term, about GD 68) compared with the adult. In 
      vitro ethanol exposure (50 and 100 mM) decreased hippocampal CO formation in the 
      GD 62 fetus, which was prevented by incubation with 500 microM L-glutamate.
FAU - Cook, M N
AU  - Cook MN
AD  - Department of Pharmacology and Toxicology, Faculty of Medicine, Queen's 
      University, Kingston, Ont., Canada.
FAU - Marks, G S
AU  - Marks GS
FAU - Vreman, H J
AU  - Vreman HJ
FAU - McLaughlin, B E
AU  - McLaughlin BE
FAU - Nakatsu, K
AU  - Nakatsu K
FAU - Stevenson, D K
AU  - Stevenson DK
FAU - Brien, J F
AU  - Brien JF
LA  - eng
GR  - HD 14426/HD/NICHD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Brain Res Dev Brain Res
JT  - Brain research. Developmental brain research
JID - 8908639
RN  - 0 (Central Nervous System Depressants)
RN  - 3K9958V90M (Ethanol)
RN  - 7U1EE4V452 (Carbon Monoxide)
SB  - IM
MH  - Animals
MH  - Carbon Monoxide/*metabolism
MH  - Central Nervous System Depressants/*pharmacology
MH  - Ethanol/*pharmacology
MH  - Female
MH  - Guinea Pigs
MH  - Hippocampus/drug effects/*growth & development/*metabolism
MH  - In Vitro Techniques
MH  - Male
MH  - Pregnancy
EDAT- 1997/07/18 00:00
MHDA- 1997/07/18 00:01
CRDT- 1997/07/18 00:00
PHST- 1997/07/18 00:00 [pubmed]
PHST- 1997/07/18 00:01 [medline]
PHST- 1997/07/18 00:00 [entrez]
AID - S0165-3806(97)00063-1 [pii]
AID - 10.1016/s0165-3806(97)00063-1 [doi]
PST - ppublish
SO  - Brain Res Dev Brain Res. 1997 Jul 18;101(1-2):283-6. doi: 
      10.1016/s0165-3806(97)00063-1.