PMID- 9263874
OWN - NLM
STAT- MEDLINE
DCOM- 19971009
LR  - 20071115
IS  - 0966-8519 (Print)
IS  - 0966-8519 (Linking)
VI  - 6
IP  - 4
DP  - 1997 Jul
TI  - The Bicarbon heart valve prosthesis: short-term results.
PG  - 410-5
AB  - BACKGROUND AND AIMS OF THE STUDY: To determine the short-term results of the 
      Bicarbon (Sorin Biomedica, Saluggia, Italy) heart valve prosthesis at our 
      institution. METHODS: Between November 1991 and December 1995, 256 patients (mean 
      age 59.9 +/- 9.8 years) underwent valve replacement with a Bicarbon valve 
      prosthesis. The mean ejection fraction was 60 +/- 14.8% and the mean left 
      ventricular end-diastolic pressure 15.9 +/- 8.7 mmHg. Redo (n = 61) and combined 
      procedures (n = 72) were included in this study; mixed types of prostheses were 
      excluded. The procedures were divided into groups: aortic valve replacement (n = 
      163), mitral valve replacement (n = 60) and aortic-mitral (double) valve 
      replacement (n = 33). Kaplan-Meier survival analysis was performed and predictors 
      for survival were tested univariately and multivariately. RESULTS: The mean 
      follow up was 30 +/- 25.1 months with a total of 7,696 patient-months (641.3 
      patient-years) and was 100% complete. The Kaplan-Meier survival rate at 48 months 
      was 87 +/- 2%. The valve-related morbidity expressed as linearized incidence rate 
      (% per patient-year) was: anticoagulation bleeding 2.3 +/- 0.6; thromboembolic 
      event 1.0 +/- 0.4; periprosthetic leak 0.6 +/- 0.3; and endocarditis 0.3 +/- 0.2. 
      Univariate significant factors for worse survival were: higher preoperative New 
      York Heart Association (NYHA) functional class, valve implantation site, presence 
      of associated operation, increasing age, decreasing ejection fraction, longer 
      aortic cross-clamp time, and longer cardiopulmonary bypass time. In multivariate 
      analysis longer aortic cross-clamp time and higher preoperative NYHA 
      classification were significant independent predictors. CONCLUSIONS: These good 
      short-term results after Bicarbon valve replacement are encouraging and 
      comparable with those obtained with other bileaflet mechanical heart valves. 
      However, further follow up is mandatory.
FAU - Casselman, F
AU  - Casselman F
AD  - Department of Cardiac Surgery, University Hospital Gasthuisberg, Leuven, Belgium.
FAU - Herijgers, P
AU  - Herijgers P
FAU - Meyns, B
AU  - Meyns B
FAU - Flameng, W
AU  - Flameng W
FAU - Daenen, W
AU  - Daenen W
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PL  - England
TA  - J Heart Valve Dis
JT  - The Journal of heart valve disease
JID - 9312096
RN  - 0 (Biocompatible Materials)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Analysis of Variance
MH  - Aortic Valve/*surgery
MH  - *Biocompatible Materials
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Valve Diseases/mortality/physiopathology/surgery
MH  - *Heart Valve Prosthesis
MH  - Hemodynamics/physiology
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve/*surgery
MH  - Multivariate Analysis
MH  - Postoperative Complications/mortality
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Prosthesis Design
MH  - Survival Analysis
MH  - Time Factors
EDAT- 1997/07/01 00:00
MHDA- 1997/07/01 00:01
CRDT- 1997/07/01 00:00
PHST- 1997/07/01 00:00 [pubmed]
PHST- 1997/07/01 00:01 [medline]
PHST- 1997/07/01 00:00 [entrez]
PST - ppublish
SO  - J Heart Valve Dis. 1997 Jul;6(4):410-5.