PMID- 9280694
OWN - NLM
STAT- MEDLINE
DCOM- 19970904
LR  - 20161124
IS  - 0012-0472 (Print)
IS  - 0012-0472 (Linking)
VI  - 122
IP  - 27
DP  - 1997 Jul 4
TI  - [The extent of diastolic dysfunction and its correlation with subjective 
      impairment of physical capacity in dilated cardiomyopathy].
PG  - 845-8
AB  - OBJECTIVE: To find out whether in patients with dilated cardiomyopathy (DCM) 
      there is a correlation between subjective reduction in physical capacity and the 
      transmitral Doppler profile as a measure of left ventricular (LV) filling. 
      PATIENTS AND METHODS: 30 consecutive patients (24 men, six women; average age 55 
      +/- 2 years) with chronic primary DCM were examined by Doppler echocardiography 
      to determine possible differences in LV filling pattern, in correlation with 
      subjective impairment of physical capacity graded according to the New York Heart 
      Association (NYHA) classification. RESULTS: Mean LV ejection fraction was 34 +/- 
      1%. All patients were in sinus rhythm. Eight patients, in NYHA class I had nearly 
      normal LV filling (E wave 79 m/s, A wave 0.76 m/s); 11 patients in class II had 
      impaired relaxation (E wave 0.77 m/s. A wave 0.82 m/s) and 11 in class III/V had 
      a restricted filling pattern (E wave 0.98 m/s. A wave 0.57 m/s). There was a 
      significant difference between class II and class III/IV patients with regard to 
      E wave deceleration time (0.15 and 0.11 s, respectively; P < 0.05), as well as 
      between class I and class III/IV patients (0.18 and 0.11 s, respectively; P < 
      0.05). The A wave deceleration time was clearly shorter in class III/IV than 
      class II (0.08 s and 0.11 s; P < 0.05) and class I patients (0.08 s and 0.10 s; P 
      < 0.05). CONCLUSIONS: The extent of LV diastolic dysfunction correlated with 
      subjective physical capacity. The more the LV filling pattern had changed from 
      normal towards restricted, the greater the patient's symptoms.
FAU - Fruhwald, F M
AU  - Fruhwald FM
AD  - Abteilung fur Kardiologie, Medizinische Klinik, Karl-Franzens-Universitat Graz. 
      friedrich.fruhwald@kfunigraz.oc.at
FAU - Watzinger, N
AU  - Watzinger N
FAU - Schumacher, M
AU  - Schumacher M
FAU - Zweiker, R
AU  - Zweiker R
FAU - Pokan, R
AU  - Pokan R
FAU - Klein, W
AU  - Klein W
LA  - ger
PT  - Journal Article
TT  - Das Ausmass der diastolischen Dysfunktion und dessen Korrelation zur subjektiven 
      Leistungseinschrankung bei dilativer Kardiomyopathie.
PL  - Germany
TA  - Dtsch Med Wochenschr
JT  - Deutsche medizinische Wochenschrift (1946)
JID - 0006723
SB  - IM
MH  - Cardiomyopathy, Dilated/classification/diagnostic imaging/*physiopathology
MH  - Chronic Disease
MH  - Diastole
MH  - Echocardiography, Doppler/methods/statistics & numerical data
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Physical Fitness/*physiology
MH  - Prognosis
MH  - Systole
MH  - Ventricular Dysfunction, Left/classification/diagnostic imaging/physiopathology
EDAT- 1997/07/04 00:00
MHDA- 1997/07/04 00:01
CRDT- 1997/07/04 00:00
PHST- 1997/07/04 00:00 [pubmed]
PHST- 1997/07/04 00:01 [medline]
PHST- 1997/07/04 00:00 [entrez]
AID - 10.1055/s-2008-1047698 [doi]
PST - ppublish
SO  - Dtsch Med Wochenschr. 1997 Jul 4;122(27):845-8. doi: 10.1055/s-2008-1047698.