PMID- 9283600
OWN - NLM
STAT- MEDLINE
DCOM- 19970917
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 97
IP  - 2
DP  - 1997 Sep
TI  - Identification of pericentric inversion 12, inv(12)(p13.1q11), by fluorescence in 
      situ hybridization in a patient with acute myeloid leukemia (AML-M6).
PG  - 157-60
AB  - Using probes located between 12p12.1 and 12p13.3, we performed fluorescence in 
      situ hybridization (FISH) analysis and identified an inv(12)(p13.1q11) in a 
      patient with acute myeloid leukemia (AML-M6). Standard cytogenetic analysis had 
      identified the rearranged chromosomes 12 as del(12) (p11p13). Although deletions 
      and translocations involving band 12p13 are fairly common chromosomal 
      abnormalities observed in a broad spectrum of hematologic malignancies, inv(12) 
      is a rather rare abnormality. We compare the clinical and cytogenetic findings 
      with those of the previous cases reported in the literature.
FAU - Sato, Y
AU  - Sato Y
AD  - Section of Hematology/Oncology, University of Chicago, IL 60637, USA.
FAU - Bohlander, S K
AU  - Bohlander SK
FAU - Kobayashi, H
AU  - Kobayashi H
FAU - Suto, Y
AU  - Suto Y
FAU - Davis, E M
AU  - Davis EM
FAU - Espinosa, R 3rd
AU  - Espinosa R 3rd
FAU - Le Beau, M M
AU  - Le Beau MM
FAU - Rowley, J D
AU  - Rowley JD
LA  - eng
GR  - CA40046/CA/NCI NIH HHS/United States
GR  - CA42557/CA/NCI NIH HHS/United States
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
RN  - 0 (DNA Probes)
SB  - IM
MH  - Chromosome Banding
MH  - *Chromosome Inversion
MH  - Chromosome Mapping
MH  - *Chromosomes, Human, Pair 12
MH  - DNA Probes
MH  - Female
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Leukemia, Erythroblastic, Acute/*genetics
MH  - Middle Aged
EDAT- 1997/09/01 00:00
MHDA- 2001/03/28 10:01
CRDT- 1997/09/01 00:00
PHST- 1997/09/01 00:00 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1997/09/01 00:00 [entrez]
AID - S0165460896003354 [pii]
AID - 10.1016/s0165-4608(96)00335-4 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1997 Sep;97(2):157-60. doi: 
      10.1016/s0165-4608(96)00335-4.