PMID- 9287189
OWN - NLM
STAT- MEDLINE
DCOM- 19971113
LR  - 20190914
IS  - 0952-7915 (Print)
IS  - 0952-7915 (Linking)
VI  - 9
IP  - 4
DP  - 1997 Aug
TI  - Role of dendritic and follicular dendritic cells in HIV infection and 
      pathogenesis.
PG  - 563-7
AB  - Dendritic cells (DCs) and follicular dendritic cells (FDCs) play important roles 
      in HIV-mediated pathogenesis. Recent studies have defined new DC subsets and 
      shown that DCs in lymphoid mucosa can both harbor virus and stimulate its spread 
      into CD4(+) T cells. FDCs harbor unspliced HIV mRNA and immune complexed virus, 
      but not actively infectious virus, yet these cells are a key regulated reservoir 
      of virions.
FAU - Grouard, G
AU  - Grouard G
AD  - Regional Primate Research Center, Department of Microbiology, University of 
      Washington Medical Center, Seattle, WA 98195, USA.
FAU - Clark, E A
AU  - Clark EA
LA  - eng
GR  - GM37905/GM/NIGMS NIH HHS/United States
GR  - RR00166/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PT  - Review
PL  - England
TA  - Curr Opin Immunol
JT  - Current opinion in immunology
JID - 8900118
RN  - 0 (HIV Antigens)
RN  - 0 (RNA, Messenger)
RN  - 0 (RNA, Viral)
RN  - 0 (Receptors, Virus)
SB  - IM
CIN - Curr Opin Immunol. 1997 Aug;9(4):549-50. PMID: 9287181
MH  - Antigen Presentation
MH  - Dendritic Cells/*immunology/virology
MH  - HIV/*physiology
MH  - HIV Antigens/immunology
MH  - HIV Infections/etiology/*immunology
MH  - Humans
MH  - Lymph Nodes/immunology/ultrastructure
MH  - Mucous Membrane/immunology/pathology
MH  - RNA, Messenger/metabolism
MH  - RNA, Viral/metabolism
MH  - Receptors, Virus/physiology
MH  - Virion/physiology
MH  - Virus Replication
RF  - 41
EDAT- 1997/08/01 00:00
MHDA- 1997/08/01 00:01
CRDT- 1997/08/01 00:00
PHST- 1997/08/01 00:00 [pubmed]
PHST- 1997/08/01 00:01 [medline]
PHST- 1997/08/01 00:00 [entrez]
AID - S0952-7915(97)80111-2 [pii]
AID - 10.1016/s0952-7915(97)80111-2 [doi]
PST - ppublish
SO  - Curr Opin Immunol. 1997 Aug;9(4):563-7. doi: 10.1016/s0952-7915(97)80111-2.