PMID- 9288362
OWN - NLM
STAT- MEDLINE
DCOM- 19971023
LR  - 20220318
IS  - 0192-415X (Print)
IS  - 0192-415X (Linking)
VI  - 25
IP  - 2
DP  - 1997
TI  - Effects of siegesbeckia pubescens on immediate hypersensitivity reaction.
PG  - 163-7
AB  - This study was carried out to examine the effect of an aqueous extract from 
      Siegesbeckia pubescens (Compositae) (SPAE) on immunoglobulin E (IgE)-mediated 
      immediate hypersensitivity reaction. Forty-eight hours passive cutaneous 
      anaphylaxis in rats was significantly inhibited by oral administration of SPAE 
      (100 micrograms/g). It also inhibited histamine release from rat peritoneal mast 
      cells induced by anti-dinitrophenyl (DNP)-IgE and DNP-human serum albumin. The 
      data indicate that SPAE has antiallergic activity, and that its action may be due 
      to inhibition of histamine release from mast cells.
FAU - Kim, H M
AU  - Kim HM
AD  - Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan, 
      Chonbuk, South Korea.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Singapore
TA  - Am J Chin Med
JT  - The American journal of Chinese medicine
JID - 7901431
SB  - IM
MH  - Animals
MH  - Hypersensitivity/*drug therapy
MH  - Mast Cells/drug effects
MH  - *Medicine, East Asian Traditional
MH  - Rats
MH  - Rats, Sprague-Dawley
EDAT- 1997/01/01 00:00
MHDA- 1997/01/01 00:01
CRDT- 1997/01/01 00:00
PHST- 1997/01/01 00:00 [pubmed]
PHST- 1997/01/01 00:01 [medline]
PHST- 1997/01/01 00:00 [entrez]
AID - S0192415X97000184 [pii]
AID - 10.1142/S0192415X97000184 [doi]
PST - ppublish
SO  - Am J Chin Med. 1997;25(2):163-7. doi: 10.1142/S0192415X97000184.