PMID- 9294918
OWN - NLM
STAT- MEDLINE
DCOM- 19971001
LR  - 20150901
IS  - 0578-1337 (Print)
IS  - 0578-1337 (Linking)
VI  - 59
IP  - 6
DP  - 1997 Jun
TI  - Allogeneic bone marrow transplantation for Gaucher disease--a case report.
PG  - 372-6
AB  - A Chinese patient who presented painful disability of right hip was diagnosed as 
      having type 1 Gaucher disease four years later when hepatosplenomegaly was found. 
      Splenectomy was performed but her condition did not improve. So human leukocyte 
      antigen (HLA)-matched sibling allogeneic bone marrow transplantation (BMT) was 
      performed. The transplantation course was smooth. Although her bone marrow was in 
      mixed chimeric state, symptoms disappeared and her growth caught up with normal 
      level after BMT. Gaucher disease should be considered in cases with 
      hepatosplenomegaly and bone disorder of unknown causes. Allogeneic BMT is an 
      effective treatment, but the treatment-related risk should be seriously evaluated 
      and the late complications should be closely monitored.
FAU - Yen, C C
AU  - Yen CC
AD  - Department of Medicine, Veterans General Hospital-Taipei, Taiwan, R.O.C.
FAU - Chiou, T J
AU  - Chiou TJ
FAU - Lin, C Y
AU  - Lin CY
FAU - Wang, N H
AU  - Wang NH
FAU - Chen, P M
AU  - Chen PM
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - China (Republic : 1949- )
TA  - Zhonghua Yi Xue Za Zhi (Taipei)
JT  - Zhonghua yi xue za zhi = Chinese medical journal; Free China ed
JID - 0005327
SB  - IM
MH  - *Bone Marrow Transplantation
MH  - Child, Preschool
MH  - Female
MH  - Gaucher Disease/*therapy
MH  - Humans
MH  - Transplantation, Homologous
EDAT- 1997/06/01 00:00
MHDA- 1997/09/19 00:01
CRDT- 1997/06/01 00:00
PHST- 1997/06/01 00:00 [pubmed]
PHST- 1997/09/19 00:01 [medline]
PHST- 1997/06/01 00:00 [entrez]
PST - ppublish
SO  - Zhonghua Yi Xue Za Zhi (Taipei). 1997 Jun;59(6):372-6.