PMID- 9303755
OWN - NLM
STAT- MEDLINE
DCOM- 19970925
LR  - 20161020
IS  - 1026-3470 (Print)
IS  - 1026-3470 (Linking)
IP  - 3
DP  - 1997 May-Jun
TI  - [A method of using synergists in studying the level of activity of enzyme systems 
      and their participation in the mechanism of action of insecticides on insects].
PG  - 320-8
AB  - An indirect toxicology method was used to assess the monooxygenase (MO) and 
      nonspecific esterase (NE) activities in three synanthropic cockroach species and 
      four races of houseflies with the help of common and novel organophosphorus and 
      pyrethroid synergists: piperonyl butoxide (PB), S,S,S-tributyltrithiophosphate 
      (TBTP), Kitazin-P, Karesan, butylmercapto-2-thio-1,3,2-oxazaphosphorinan (AO-6), 
      and 2-phenylmercapto-2-thio-1,3,2-oxazaphosphorinan (AO-2). The relationship 
      between the coefficient of synergistic effect (CSE) and the concentrations of MO 
      and NE inhibitors was described, and the minimum effective concentrations with 
      the highest synergistic effect were determined. These concentrations are 
      advisable for use in the insect enzyme assays and studies of insecticide 
      detoxification and insect resistance to them.
FAU - Eremina, O Iu
AU  - Eremina OIu
FAU - Roslavtseva, S A
AU  - Roslavtseva SA
LA  - rus
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
TT  - K metodike ispol'zovaniia sinergistov pri izuchenii urovnia aktivnosti nekotorykh 
      fermentnykh sistem i ikh uchastiia v mekhanizme deistviia insektitsidov na 
      nasekomykh.
PL  - Russia (Federation)
TA  - Izv Akad Nauk Ser Biol
JT  - Izvestiia Akademii nauk. Seriia biologicheskaia
JID - 9300152
RN  - 0 (Enzyme Inhibitors)
RN  - 0 (Insecticides)
RN  - 0 (Pyrethrins)
RN  - 509F88P9SZ (Permethrin)
RN  - EC 1.13.- (Oxygenases)
RN  - EC 3.1.1.- (Carboxylic Ester Hydrolases)
RN  - EC 3.1.1.1 (Carboxylesterase)
RN  - U5N7SU872W (Malathion)
SB  - IM
MH  - Animals
MH  - Carboxylesterase
MH  - Carboxylic Ester Hydrolases/drug effects
MH  - Cockroaches/drug effects/*enzymology
MH  - Dose-Response Relationship, Drug
MH  - Drug Synergism
MH  - Enzyme Inhibitors/*pharmacology
MH  - Houseflies/drug effects/*enzymology
MH  - Insecticide Resistance
MH  - Insecticides/*pharmacology
MH  - Malathion/*pharmacology
MH  - Oxygenases/drug effects
MH  - Permethrin
MH  - Pyrethrins/*pharmacology
EDAT- 1997/05/01 00:00
MHDA- 1997/09/26 00:01
CRDT- 1997/05/01 00:00
PHST- 1997/05/01 00:00 [pubmed]
PHST- 1997/09/26 00:01 [medline]
PHST- 1997/05/01 00:00 [entrez]
PST - ppublish
SO  - Izv Akad Nauk Ser Biol. 1997 May-Jun;(3):320-8.