PMID- 9307322
OWN - NLM
STAT- MEDLINE
DCOM- 19980107
LR  - 20190822
IS  - 0378-5955 (Print)
IS  - 0378-5955 (Linking)
VI  - 111
IP  - 1-2
DP  - 1997 Sep
TI  - Rate and adaptation effects on the auditory evoked brainstem response in human 
      newborns and adults.
PG  - 165-76
AB  - Auditory evoked brainstem response (ABR) latencies increased and amplitudes 
      decreased with increasing stimulus repetition rate for human newborns and adults. 
      The wave V latency increases were larger for newborns than adults. The wave V 
      amplitude decreases were smaller for newborns than adults. These differences 
      could not be explained by developmental differences in frequency responsivity. 
      The transition from the unadapted to the fully adapted response was less rapid in 
      newborns than adults at short (= 10 ms) inter stimulus intervals (ISIs). At 
      longer ISIs (= 20 ms) there were no developmental differences in the transition 
      to the fully adapted response. The newborn transition occurred in a two stage 
      process. The rapid initial stage observed in adults and newborns was complete by 
      about 40 ms. A second slower stage was observed only in newborns although it has 
      been observed in adults in other studies (Weatherby and Hecox, 1982; Lightfoot, 
      1991; Lasky et al., 1996). These effects were replicated at different stimulus 
      intensities. After the termination of stimulation the return to the wave V 
      unadapted response took nearly 500 ms in newborns. Neither the newborn nor the 
      adult data can be explained by forward masking of one click on the next click. 
      These results indicate human developmental differences in adaptation to 
      repetitive auditory stimulation at the level of the brainstem.
FAU - Lasky, R E
AU  - Lasky RE
AD  - The University of Wisconsin-Madison Medical School, Department of Neurology, 
      53792-5132, USA.
LA  - eng
GR  - R01 NS20647-01A1/NS/NINDS NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Hear Res
JT  - Hearing research
JID - 7900445
SB  - IM
MH  - Acoustic Stimulation
MH  - Adolescent
MH  - Adult
MH  - Aging/*physiology
MH  - Auditory Threshold/physiology
MH  - Brain Stem/*growth & development
MH  - Evoked Potentials, Auditory, Brain Stem/*physiology
MH  - Humans
MH  - Infant, Newborn
MH  - Linear Models
EDAT- 1997/11/05 00:00
MHDA- 1997/11/05 00:01
CRDT- 1997/11/05 00:00
PHST- 1997/11/05 00:00 [pubmed]
PHST- 1997/11/05 00:01 [medline]
PHST- 1997/11/05 00:00 [entrez]
AID - S0378-5955(97)00106-8 [pii]
AID - 10.1016/s0378-5955(97)00106-8 [doi]
PST - ppublish
SO  - Hear Res. 1997 Sep;111(1-2):165-76. doi: 10.1016/s0378-5955(97)00106-8.