PMID- 9309113
OWN - NLM
STAT- MEDLINE
DCOM- 19971015
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 98
IP  - 1
DP  - 1997 Oct 1
TI  - Unbalanced X;autosome translocation (X;18)(q13;p11) in a case of aggressive 
      natural killer non-Hodgkin lymphoma.
PG  - 16-9
AB  - Recent evidence has shown that rare cases of aggressive non-Hodgkin lymphomas 
      (NHL) derive from cells belonging to the natural killer (NK) lymphocyte lineage 
      and a new clinico pathologic entity has been proposed. Though well documented in 
      B- and T-cell NHL, chromosome abnormalities are rare findings in NK-NHL and to 
      date, no recurrent cytogenetic abnormality has been described. The present study 
      reports the clinical data, cytogenetic and fluorescence in situ hybridization 
      (FISH) analysis of a new case of typical NK-NHL characterized by a primary 
      unbalanced translocation (X;18) (q13;p11). Recent data of X;autosome 
      translocation in malignant lymphomas have proposed Xp22 and Xq28 as the location 
      of NHL-related oncogenes. According to other published reports on the involvement 
      of the Xq13 region in NHL and particularly in aggressive forms, we hypothesize 
      the existence of additional putative lymphoma-associated oncogenes at the band 
      Xq13.
FAU - Callet-Bauchu, E
AU  - Callet-Bauchu E
AD  - Laboratoire Central d'Hematologie, Centre Hospitalier Lyon Sud, Pierre-Benite, 
      France.
FAU - Rimokh, R
AU  - Rimokh R
FAU - Gazzo, S
AU  - Gazzo S
FAU - Pages, J
AU  - Pages J
FAU - Bastion, Y
AU  - Bastion Y
FAU - Berger, F
AU  - Berger F
FAU - Coeur, P
AU  - Coeur P
FAU - Felman, P
AU  - Felman P
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
SB  - IM
MH  - Adult
MH  - Cell Lineage
MH  - *Chromosomes, Human, Pair 18
MH  - Female
MH  - Humans
MH  - Immunophenotyping
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Killer Cells, Natural/*immunology
MH  - Lymphoma, Non-Hodgkin/*genetics/immunology/pathology
MH  - *Translocation, Genetic
MH  - *X Chromosome
EDAT- 1997/10/06 00:00
MHDA- 1997/10/06 00:01
CRDT- 1997/10/06 00:00
PHST- 1997/10/06 00:00 [pubmed]
PHST- 1997/10/06 00:01 [medline]
PHST- 1997/10/06 00:00 [entrez]
AID - S0165460896004086 [pii]
AID - 10.1016/s0165-4608(96)00408-6 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1997 Oct 1;98(1):16-9. doi: 
      10.1016/s0165-4608(96)00408-6.